Controversies related to the cardiac origin of preeclampsia – Does a mother's heart know?

IF 3.9 2区医学 Q1 OBSTETRICS & GYNECOLOGY

Best Practice & Research Clinical Obstetrics & Gynaecology Pub Date : 2025-03-01 DOI:10.1016/j.bpobgyn.2025.102600

Eric J. Stöhr

引用次数: 0

Abstract

A potential role of cardiac output has been proposed in the development of preeclampsia. Given that cardiac output may contribute to hypertensive states in the general population, a contribution from cardiac output to preeclampsia is plausible. However, the interplay between the heart and the periphery is complex, and some responses in cardiac output during pregnancy are surprising even when pregnancy progresses without complications. Therefore, this review focuses on recent evidence that has provided new insight into cardiac output in healthy humans including pregnancy, and offers some suggestions about future studies in preeclamptic patients.

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子痫前期心脏起源的争议——母亲的心脏知道吗？

心排血量在子痫前期发展中的潜在作用已被提出。鉴于心输出量可能导致一般人群的高血压状态，心输出量对子痫前期的贡献是可信的。然而，心脏和外周之间的相互作用是复杂的，即使在妊娠无并发症的情况下，妊娠期间心输出量的一些反应也是令人惊讶的。因此，本文综述了最近对包括妊娠在内的健康人心输出量的研究提供的新证据，并对未来在子痫前期患者中的研究提出了一些建议。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Best Practice & Research Clinical Obstetrics & Gynaecology 医学-妇产科学

CiteScore

9.40

自引率

1.80%

发文量

113

审稿时长

54 days

期刊介绍： In practical paperback format, each 200 page topic-based issue of Best Practice & Research Clinical Obstetrics & Gynaecology will provide a comprehensive review of current clinical practice and thinking within the specialties of obstetrics and gynaecology. All chapters take the form of practical, evidence-based reviews that seek to address key clinical issues of diagnosis, treatment and patient management. Each issue follows a problem-orientated approach that focuses on the key questions to be addressed, clearly defining what is known and not known. Management will be described in practical terms so that it can be applied to the individual patient.