The development and application of SERS-based lateral flow immunochromatography in the field of food safety

IF 5.3 2区化学 Q1 CHEMISTRY, ANALYTICAL

Microchimica Acta Pub Date : 2025-03-21 DOI:10.1007/s00604-025-07047-7

Wenxi Liu, Hao Wang, Wenhui Zhong, Yichun Zhang, Yingyue Liu, Xibao Gao, Mengmeng Yan, Chao Zhu

{"title":"The development and application of SERS-based lateral flow immunochromatography in the field of food safety","authors":"Wenxi Liu, Hao Wang, Wenhui Zhong, Yichun Zhang, Yingyue Liu, Xibao Gao, Mengmeng Yan, Chao Zhu","doi":"10.1007/s00604-025-07047-7","DOIUrl":null,"url":null,"abstract":"<div><p>Surface-Enhanced Raman Scattering-Lateral Flow Immunoassay (SERS-LFIA) inherits the advantages of simplicity, rapidness, and stability from Lateral Flow Immunoassay (LFIA), while integrating the sensitivity and accuracy of SERS, thereby attracting extensive attention in the field of food safety monitoring. This paper delves into the design strategies and principles underlying SERS-LFIA, introducing the detection formats based on SERS and contrasting the differences between traditional Raman molecules and those located in the Raman-silent region. It analyzes two immunoassay methods, namely sandwich and competitive, along with their respective applications. Importantly, by reviewing the applications of SERS-LFIA in food safety monitoring over the past 5 years, this paper summarizes the challenges faced by SERS-LFIA technology in practical applications and development. Furthermore, it provides a forward-looking perspective on the future development of SERS-LFIA. As a pivotal analytical method in the field of food safety monitoring, SERS-LFIA is demonstrating immense potential. It is hoped that this paper will offer valuable insights for the future development and application of SERS-LFIA.</p><h3>Graphical Abstract</h3>\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 4","pages":""},"PeriodicalIF":5.3000,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00604-025-07047-7.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microchimica Acta","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s00604-025-07047-7","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}

引用次数: 0

Abstract

Surface-Enhanced Raman Scattering-Lateral Flow Immunoassay (SERS-LFIA) inherits the advantages of simplicity, rapidness, and stability from Lateral Flow Immunoassay (LFIA), while integrating the sensitivity and accuracy of SERS, thereby attracting extensive attention in the field of food safety monitoring. This paper delves into the design strategies and principles underlying SERS-LFIA, introducing the detection formats based on SERS and contrasting the differences between traditional Raman molecules and those located in the Raman-silent region. It analyzes two immunoassay methods, namely sandwich and competitive, along with their respective applications. Importantly, by reviewing the applications of SERS-LFIA in food safety monitoring over the past 5 years, this paper summarizes the challenges faced by SERS-LFIA technology in practical applications and development. Furthermore, it provides a forward-looking perspective on the future development of SERS-LFIA. As a pivotal analytical method in the field of food safety monitoring, SERS-LFIA is demonstrating immense potential. It is hoped that this paper will offer valuable insights for the future development and application of SERS-LFIA.

Graphical Abstract

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Microchimica Acta 化学-分析化学

CiteScore

9.80

自引率

5.30%

发文量

410

审稿时长

2.7 months

期刊介绍： As a peer-reviewed journal for analytical sciences and technologies on the micro- and nanoscale, Microchimica Acta has established itself as a premier forum for truly novel approaches in chemical and biochemical analysis. Coverage includes methods and devices that provide expedient solutions to the most contemporary demands in this area. Examples are point-of-care technologies, wearable (bio)sensors, in-vivo-monitoring, micro/nanomotors and materials based on synthetic biology as well as biomedical imaging and targeting.