Genetic Polymorphisms and Their Association With Endodontic Postoperative Pain: A Systematic Review.

IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE
Ertuğrul Karataş, Çiğdem Yüce Kahraman, Hussna Khan, Zehra Yonel
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引用次数: 0

Abstract

The present systematic review aims to investigate whether currently available evidence supports a possible association between Single Nucleotide Polymorphism (SNP) and the level of Endodontic Postoperative Pain (EPP). Studies including human participants and those evaluating the association between SNPs and EPP were included. A total of 618 articles were identified following the initial search of electronic databases. Of these, 50 were found in Scopus, 13 in PubMed, 26 in Web of Science, and 529 in Google Scholar databases. Out of the 4 included studies, 3 reported a significant association between the selected SNPs and EPP. The present systematic review suggests that there is a possible association between genetic polymorphisms and the level of pain following root canal treatment. However, it is impossible to conclude that a specific SNP is associated with EPP based on the included studies investigating different genes and SNPs with a small sample size.

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来源期刊
Australian Endodontic Journal
Australian Endodontic Journal DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
3.50
自引率
6.20%
发文量
99
审稿时长
>12 weeks
期刊介绍: The Australian Endodontic Journal provides a forum for communication in the different fields that encompass endodontics for all specialists and dentists with an interest in the morphology, physiology, and pathology of the human tooth, in particular the dental pulp, root and peri-radicular tissues. The Journal features regular clinical updates, research reports and case reports from authors worldwide, and also publishes meeting abstracts, society news and historical endodontic glimpses. The Australian Endodontic Journal is a publication for dentists in general and specialist practice devoted solely to endodontics. It aims to promote communication in the different fields that encompass endodontics for those dentists who have a special interest in endodontics.
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