Ertuğrul Karataş, Çiğdem Yüce Kahraman, Hussna Khan, Zehra Yonel
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引用次数: 0
Abstract
The present systematic review aims to investigate whether currently available evidence supports a possible association between Single Nucleotide Polymorphism (SNP) and the level of Endodontic Postoperative Pain (EPP). Studies including human participants and those evaluating the association between SNPs and EPP were included. A total of 618 articles were identified following the initial search of electronic databases. Of these, 50 were found in Scopus, 13 in PubMed, 26 in Web of Science, and 529 in Google Scholar databases. Out of the 4 included studies, 3 reported a significant association between the selected SNPs and EPP. The present systematic review suggests that there is a possible association between genetic polymorphisms and the level of pain following root canal treatment. However, it is impossible to conclude that a specific SNP is associated with EPP based on the included studies investigating different genes and SNPs with a small sample size.
本系统综述旨在调查目前可用的证据是否支持单核苷酸多态性（SNP）与牙髓术后疼痛（EPP）水平之间可能的关联。包括人类参与者和评估snp与EPP之间关系的研究。在初步检索电子数据库后，共确定了618篇文章。其中，Scopus收录50篇，PubMed收录13篇，Web Of Science收录26篇，b谷歌Scholar收录529篇。在纳入的4项研究中，3项报告了所选snp与EPP之间的显著关联。目前的系统综述表明，遗传多态性与根管治疗后疼痛程度之间可能存在关联。然而，基于所纳入的调查不同基因和SNP的小样本量研究，无法得出特定SNP与EPP相关的结论。
期刊介绍：
The Australian Endodontic Journal provides a forum for communication in the different fields that encompass endodontics for all specialists and dentists with an interest in the morphology, physiology, and pathology of the human tooth, in particular the dental pulp, root and peri-radicular tissues.
The Journal features regular clinical updates, research reports and case reports from authors worldwide, and also publishes meeting abstracts, society news and historical endodontic glimpses.
The Australian Endodontic Journal is a publication for dentists in general and specialist practice devoted solely to endodontics. It aims to promote communication in the different fields that encompass endodontics for those dentists who have a special interest in endodontics.
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