[Clinical analysis of nutritional components in children with acute leukemia].

Q3 Medicine

中国当代儿科杂志 Pub Date : 2025-03-15 DOI:10.7499/j.issn.1008-8830.2408102

Li-Xia Shi, Ming-Zhong Zhao, Fei-Fei Wang, Yu-Qian Xing, Hong-Yan Ji, Ping Zhao

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引用次数: 0

Abstract

Objectives: To assess the changes in body composition and nutritional risks faced by children with different stages of acute leukemia (AL).

Methods: Bioelectrical impedance analysis combined with anthropometric measurements was used to detect body composition. This prospective study was conducted from August 2023 to July 2024 at Shandong Provincial Hospital, examining the body composition and physical balance of children with various stages of AL and healthy children.

Results: The non-fat components of children with AL and healthy children both showed a linear increase with age. In the younger age group, there were no significant differences in body composition between children with AL and healthy children. However, in the older age group, the body composition of children undergoing chemotherapy for AL was significantly lower than that of healthy children (P<0.05), and muscle mass recovered first after the completion of AL chemotherapy. The proportion of children with increased trunk fat in AL children who completed chemotherapy was significantly lower than that in healthy children (P<0.05), while the incidence rate of severe left-right imbalance in body composition was significantly higher (P<0.05). Muscle distribution in children with AL primarily showed insufficient limb and overall muscle mass, whereas healthy children mainly exhibited insufficient upper limb muscle mass.

Conclusions: The body composition of children with AL varies at different treatment stages, indicating that nutritional status is affected by both the disease itself and the treatment. Early screening can provide a basis for reasonable nutritional intervention.

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急性白血病患儿营养成分的临床分析

目的：探讨不同阶段急性白血病（AL）患儿的身体成分变化及营养风险。方法：采用生物电阻抗分析与人体测量相结合的方法检测人体成分。本前瞻性研究于2023年8月至2024年7月在山东省立医院进行，检测不同阶段AL患儿和健康儿童的身体组成和身体平衡。结果：AL患儿和健康儿童的非脂肪成分均随年龄的增长呈线性增加。在低龄组中，AL患儿与健康儿童的身体组成无显著差异。然而，在年龄较大的年龄组中，接受AL化疗的儿童的身体成分明显低于健康儿童（ppp）。结论：AL儿童在不同治疗阶段的身体成分不同，表明营养状况受到疾病本身和治疗的双重影响。早期筛查可为合理的营养干预提供依据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

中国当代儿科杂志 Medicine-Pediatrics, Perinatology and Child Health

CiteScore

1.50

自引率

0.00%

发文量

5006

期刊介绍： The Chinese Journal of Contemporary Pediatrics (CJCP) is a peer-reviewed open access periodical in the field of pediatrics that is sponsored by the Central South University/Xiangya Hospital of Central South University and under the auspices of the Ministry of Education of China. It is cited as a source in the scientific and technological papers of Chinese journals, the Chinese Science Citation Database (CSCD), and is one of the core Chinese periodicals in the Peking University Library. CJCP has been indexed by MEDLINE/PubMed/PMC of the American National Library, American Chemical Abstracts (CA), Holland Medical Abstracts (EM), Western Pacific Region Index Medicus (WPRIM), Scopus and EBSCO. It is a monthly periodical published on the 15th of every month, and is distributed both at home and overseas. The Chinese series publication number is CN 43-1301/R；ISSN 1008-8830. The tenet of CJCP is to “reflect the latest advances and be open to the world”. The periodical reports the most recent advances in the contemporary pediatric field. The majority of the readership is pediatric doctors and researchers.