Healthcare Professionals' Knowledge, Attitudes, and Practices Towards Stem Cell Therapy for Sarcopenia: A Cross-Sectional Study in Beijing.

IF 2.7 3区医学 Q2 HEALTH CARE SCIENCES & SERVICES

Journal of Multidisciplinary Healthcare Pub Date : 2025-03-14 eCollection Date: 2025-01-01 DOI:10.2147/JMDH.S496326

Yao Wang, Zhe Wang, Yanan Gao, Tianru Zheng, Tingting Liu

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引用次数: 0

Abstract

Background: Sarcopenia significantly impacts the aging population, and this study investigates healthcare professionals' knowledge, attitudes, and practices (KAP) towards stem cell therapy for sarcopenia.

Methods: A cross-sectional study was conducted between January 1, 2024, and March 10, 2024, in medical institutions across Beijing. The study included healthcare professionals aged 18-70 years who completed a self-designed KAP questionnaire (Cronbach's α=0.917). Positive KAP was defined as scoring above 80% of the total score for each dimension.

Results: A total of 451 healthcare professionals participated in the study, with 66.7% female and 41.0% aged 40-49 years. The knowledge, attitude, and practice were 18.00 [10.00, 24.00] (possible range: 12-24), 25.00 [23.00, 30.00] (possible range: 6-30), and 21.00 [16.00, 30.00] (possible range: 7-35), respectively. Of these respondents, 13.7% were healthcare workers in the geriatrics department, who had a positive knowledge score of 22.00 [14.00, 24.00] and a positive attitude score of 29.50 [24.00, 30.00], but their practice scores remain moderate at 27.00 [20.00, 35.00]. Additionally, 140 (31.0%) had treated sarcopenia patients within six months and 277 (61.4%) were employed at public tertiary hospitals with positive knowledge. Multivariate logistic regression indicated that not having treated patients with sarcopenia in the past six months was independently associated with poor knowledge (OR = 0.30, 95% CI: [0.15, 0.62], p = 0.001). Mediating effect analysis showed that knowledge directly affected both attitude (β = 0.475, p < 0.001) and practice (β = 0.127, p = 0.004), and indirectly influenced practice through attitude (β = 0.296, p < 0.001).

Conclusion: Healthcare professionals exhibited inadequate knowledge, positive attitudes and inactive practices towards stem cell therapy for sarcopenia. Disease-related healthcare has positive knowledge, but moderate practice. Educational programs are essential to improve knowledge and foster proactive practices among healthcare professionals regarding stem cell therapy for sarcopenia.

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医护人员对干细胞疗法治疗 "肌肉疏松症 "的认识、态度和实践：北京横断面研究。

背景：骨骼肌减少症对老龄化人口有显著影响，本研究调查了医疗保健专业人员对干细胞治疗骨骼肌减少症的知识、态度和实践（KAP）。方法：于2024年1月1日至2024年3月10日在北京市各医疗机构进行横断面研究。研究对象为18-70岁的卫生保健专业人员，他们完成了自行设计的KAP问卷（Cronbach’s α=0.917）。正向KAP定义为每个维度得分超过总分的80%。结果：共有451名医护人员参与研究，其中女性占66.7%，40-49岁占41.0%。知识、态度和行为分别为18.00[10.00,24.00]（可能范围：12-24）、25.00[23.00,30.00]（可能范围：6-30）和21.00[16.00,30.00]（可能范围：7-35）。其中，13.7%为老年科医护人员，积极知识得分为22.00分[14.00,24.00分]，积极态度得分为29.50分[24.00,30.00分]，实践得分为27.00分[20.00,35.00分]。此外，140名（31.0%）在6个月内治疗过肌肉减少症患者，277名（61.4%）在公立三级医院工作，并有积极的知识。多因素logistic回归显示，过去6个月内未接受过肌肉减少症治疗的患者与知识贫乏独立相关（OR = 0.30, 95% CI: [0.15, 0.62], p = 0.001）。中介效应分析显示，知识直接影响态度（β = 0.475, p < 0.001）和实践（β = 0.127, p = 0.004），并通过态度间接影响实践（β = 0.296, p < 0.001）。结论：医疗保健专业人员对干细胞治疗肌肉减少症的认识不足，态度积极，实践不积极。疾病相关保健有积极的认识，但有适度的实践。教育计划是必不可少的，以提高知识和促进医疗保健专业人员对干细胞治疗肌肉减少症的积极做法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Multidisciplinary Healthcare Nursing-General Nursing

CiteScore

4.60

自引率

3.00%

发文量

287

审稿时长

16 weeks

期刊介绍： The Journal of Multidisciplinary Healthcare (JMDH) aims to represent and publish research in healthcare areas delivered by practitioners of different disciplines. This includes studies and reviews conducted by multidisciplinary teams as well as research which evaluates or reports the results or conduct of such teams or healthcare processes in general. The journal covers a very wide range of areas and we welcome submissions from practitioners at all levels and from all over the world. Good healthcare is not bounded by person, place or time and the journal aims to reflect this. The JMDH is published as an open-access journal to allow this wide range of practical, patient relevant research to be immediately available to practitioners who can access and use it immediately upon publication.