Prevalence of autoimmune diabetes among Aboriginal Australians: the Fremantle Diabetes Study Phase II

IF 1.8 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
Timothy M. E. Davis, Christine S. Bundell, Stephen A. Paul Chubb, Daniel McAullay, Wendy A. Davis
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引用次数: 0

Abstract

The prevalence of autoimmune diabetes was assessed in 113 indigenous and 1555 non-indigenous participants in the Fremantle Diabetes Study Phase II. Both type 1 diabetes (3.5% vs. 8.2%) and latent autoimmune diabetes of adults diagnosed based on glutamic acid decarboxylase antibody (GADA) positivity (1.0% vs. 5.7%) were lower in Aboriginal participants (P = 0.101 and 0.039 respectively). Six Aboriginals with GADA-negative type 2 diabetes were positive for tyrosine phosphatase-related islet antigen 2 antibodies but did not exhibit relative insulin deficiency.

澳大利亚原住民自身免疫性糖尿病患病率:Fremantle糖尿病研究II期
在Fremantle糖尿病研究II期中,对113名土著和1555名非土著参与者的自身免疫性糖尿病患病率进行了评估。1型糖尿病(3.5%比8.2%)和基于谷氨酸脱羧酶抗体(GADA)阳性诊断的成人潜在自身免疫性糖尿病(1.0%比5.7%)在土著参与者中较低(P分别= 0.101和0.039)。6名gada阴性的2型糖尿病原住民酪氨酸磷酸酶相关胰岛抗原2抗体呈阳性,但未表现出相对胰岛素缺乏。
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来源期刊
Internal Medicine Journal
Internal Medicine Journal 医学-医学:内科
CiteScore
3.50
自引率
4.80%
发文量
600
审稿时长
3-6 weeks
期刊介绍: The Internal Medicine Journal is the official journal of the Adult Medicine Division of The Royal Australasian College of Physicians (RACP). Its purpose is to publish high-quality internationally competitive peer-reviewed original medical research, both laboratory and clinical, relating to the study and research of human disease. Papers will be considered from all areas of medical practice and science. The Journal also has a major role in continuing medical education and publishes review articles relevant to physician education.
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