{"title":"Comparison of 68 Ga-FAPI-04 PET/CT and 18 F-FDG PET/CT in Evaluating Lesion Stages in Constrictive Pericarditis.","authors":"Yaqun Jiang, Zhenxiong Chen, Yong He","doi":"10.1097/RLU.0000000000005843","DOIUrl":null,"url":null,"abstract":"<p><p>Constrictive pericarditis, an uncommon cause of diastolic heart failure, is reversible if identified and treated promptly and appropriately. The treatment approach may vary significantly depending on the disease stage of constrictive pericarditis. Here, we report a case of 18 F-FDG and 68 Ga-FAPI-04 PET/CT imaging in a 70-year-old woman with chronic constrictive pericarditis. The thickened pericardium showed mild uptake of 18 F-FDG but intense uptake of 68 Ga-FAPI-04, indicating that the lesion was at the fibrotic phase. This case suggests a promising role of combination of 18 F-FDG and 68 Ga-FAPI PET/CT in accurately and timely assessing the lesion stage in constrictive pericarditis.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"e631-e632"},"PeriodicalIF":9.6000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Nuclear Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/RLU.0000000000005843","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/19 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
Abstract
Constrictive pericarditis, an uncommon cause of diastolic heart failure, is reversible if identified and treated promptly and appropriately. The treatment approach may vary significantly depending on the disease stage of constrictive pericarditis. Here, we report a case of 18 F-FDG and 68 Ga-FAPI-04 PET/CT imaging in a 70-year-old woman with chronic constrictive pericarditis. The thickened pericardium showed mild uptake of 18 F-FDG but intense uptake of 68 Ga-FAPI-04, indicating that the lesion was at the fibrotic phase. This case suggests a promising role of combination of 18 F-FDG and 68 Ga-FAPI PET/CT in accurately and timely assessing the lesion stage in constrictive pericarditis.
期刊介绍:
Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty.
Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.