Ultrasound Reference Values of Ventriclo/Hemispheric Ratio and Evans Ratio Based on Most Correlated Covariates for Neonates Born at 25-41 Gestational Weeks: A Prospective Cross-Sectional Study.
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引用次数: 0
Abstract
Objectives: This study aimed to establish ultrasound reference values for the ventriculo/hemispheric ratio (V/HR) and Evans ratio in neonates between 25 and 41 weeks of gestation, based on the most correlated covariates (MCCs).
Methods: Data for V/HR and Evans ratio were collected from 1-to 7-day-old neurologically healthy neonates born or hospitalized at Hunan Provincial Maternal and Child Health Care Hospital and Yueyang Maternal and Child Health Hospital between March 2023 and September 2024. Max-min normalized quantile regressions were utilized to analyze the correlation between exploratory and dependent variables and to identify the MCCs. Reference values were established using the percentile method and MCCs, and the reliability of V/HR and Evans ratio was assessed via the intraclass correlation coefficient (ICC).
Results: A total of 1595 newborns were recruited. The V/HR median was positively correlated with the cesarean delivery (normalized regression coefficient (NRC) = 0.010, p < 0.05) but negatively correlated with the left side (NRC = -0.010, p < 0.05). The Evans ratio median was only positively correlated with the cesarean delivery (NRC = 0.010, p < 0.05). The 95th percentile (P95) of V/HR was only associated with the left side (NRC = -0.010, p < 0.05), while the P95 of the Evans ratio was unassociated with any covariates (all p > 0.05). Therefore, the MCC of V/HR at P95 was the left side, while the Evans ratio at P95 had no MCCs. The upper limits (P95) of LV/HR, RV/HR, and the Evans ratio were 0.33, 0.35, and 0.34, respectively. The ICCs of all indices exceeded 0.60, indicating moderate reliability or higher.
Conclusions: We present the reference values for LV/HR, RV/HR, and Evans ratio. The medians and P95s of V/HR and Evans ratio are NOT correlated with GA, birth weight, and age. The reliability of the V/HR and Evans ratio is up to par.
期刊介绍：
The Journal of Clinical Ultrasound (JCU) is an international journal dedicated to the worldwide dissemination of scientific information on diagnostic and therapeutic applications of medical sonography.
The scope of the journal includes--but is not limited to--the following areas: sonography of the gastrointestinal tract, genitourinary tract, vascular system, nervous system, head and neck, chest, breast, musculoskeletal system, and other superficial structures; Doppler applications; obstetric and pediatric applications; and interventional sonography. Studies comparing sonography with other imaging modalities are encouraged, as are studies evaluating the economic impact of sonography. Also within the journal''s scope are innovations and improvements in instrumentation and examination techniques and the use of contrast agents.
JCU publishes original research articles, case reports, pictorial essays, technical notes, and letters to the editor. The journal is also dedicated to being an educational resource for its readers, through the publication of review articles and various scientific contributions from members of the editorial board and other world-renowned experts in sonography.
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