Immobilization of gold nanoparticles on electrospun polyacrylonitrile/carbon nanotube nanofiber for self-powered electrochemical biosensing of myoglobin

IF 4.3 3区材料科学 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY

Materials Chemistry and Physics Pub Date : 2025-03-14 DOI:10.1016/j.matchemphys.2025.130722

Mingye Zhao , Ling Wang , Hui Xu

{"title":"Immobilization of gold nanoparticles on electrospun polyacrylonitrile/carbon nanotube nanofiber for self-powered electrochemical biosensing of myoglobin","authors":"Mingye Zhao , Ling Wang , Hui Xu","doi":"10.1016/j.matchemphys.2025.130722","DOIUrl":null,"url":null,"abstract":"<div><div>Polyacrylonitrile-carbon nanotube (PAN-CNT) nanofibers were prepared on indium tin oxide (ITO) electrode using electrospinning technique, and gold nanoparticles (AuNPs) were subsequently modified on ITO-PAN-CNT electrode by electrostatic adsorption to construct ITO-PAN-CNT–COOH–AuNPs substrate electrode. The self-powered biosensor consists of a PAN-CNT–COOH–AuNPs-aptamer functionalized biocathode and a PAN-CNT–COOH–AuNPs-glucose oxidase (GO<sub>x</sub>) bioanode. By capturing the change in electrode spatial potential resistance before and after myoglobin (Mb), This interaction affects the transmission of electrons between the redox probe [Fe(CN)<sub>6</sub>]<sup>3-</sup> an d the biocathode, establishing a linear relationship between E<sup>OCV</sup> and Mb concentration. The self-powered biosensor displayed a highly sensitive response to the target Mb over a concentration range from 5 to 5 × 10<sup>3</sup> ng mL<sup>−1</sup>, with a limit of detection reaching less than 0.23 ng mL<sup>−1</sup> (S/N = 3), and exhibited outstanding stability and selectivity.</div></div>","PeriodicalId":18227,"journal":{"name":"Materials Chemistry and Physics","volume":"339 ","pages":"Article 130722"},"PeriodicalIF":4.3000,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Materials Chemistry and Physics","FirstCategoryId":"88","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0254058425003682","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

Abstract

Polyacrylonitrile-carbon nanotube (PAN-CNT) nanofibers were prepared on indium tin oxide (ITO) electrode using electrospinning technique, and gold nanoparticles (AuNPs) were subsequently modified on ITO-PAN-CNT electrode by electrostatic adsorption to construct ITO-PAN-CNT–COOH–AuNPs substrate electrode. The self-powered biosensor consists of a PAN-CNT–COOH–AuNPs-aptamer functionalized biocathode and a PAN-CNT–COOH–AuNPs-glucose oxidase (GO_x) bioanode. By capturing the change in electrode spatial potential resistance before and after myoglobin (Mb), This interaction affects the transmission of electrons between the redox probe [Fe(CN)₆]^3- an d the biocathode, establishing a linear relationship between E^OCV and Mb concentration. The self-powered biosensor displayed a highly sensitive response to the target Mb over a concentration range from 5 to 5 × 10³ ng mL⁻¹, with a limit of detection reaching less than 0.23 ng mL⁻¹ (S/N = 3), and exhibited outstanding stability and selectivity.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Materials Chemistry and Physics 工程技术-材料科学：综合

CiteScore

8.70

自引率

4.30%

发文量

1515

审稿时长

69 days

期刊介绍： Materials Chemistry and Physics is devoted to short communications, full-length research papers and feature articles on interrelationships among structure, properties, processing and performance of materials. The Editors welcome manuscripts on thin films, surface and interface science, materials degradation and reliability, metallurgy, semiconductors and optoelectronic materials, fine ceramics, magnetics, superconductors, specialty polymers, nano-materials and composite materials.