Hossein Akbarialiabad, Parnian Jamshidi, Zahra Aminzade, Narges Azizi, Seyed Reza Taha, Najmeh Sadeghian, Lydia Johnson Kolaparambil Varghese, Mohsen Farjoud Kouhanjani, Nafise Niknam, Dora Babocs, Fatima El-Assaad, Thais Russomano, Dedee F Murrell, Shahram Paydar, Christopher G Bunick, Rowena Christiansen, M Mark Melin
{"title":"Leveraging space innovations for cancer breakthroughs on Earth.","authors":"Hossein Akbarialiabad, Parnian Jamshidi, Zahra Aminzade, Narges Azizi, Seyed Reza Taha, Najmeh Sadeghian, Lydia Johnson Kolaparambil Varghese, Mohsen Farjoud Kouhanjani, Nafise Niknam, Dora Babocs, Fatima El-Assaad, Thais Russomano, Dedee F Murrell, Shahram Paydar, Christopher G Bunick, Rowena Christiansen, M Mark Melin","doi":"10.1016/j.trecan.2025.02.003","DOIUrl":null,"url":null,"abstract":"<p><p>Space science is reshaping oncology by providing novel insights into cancer biology, diagnostics, and therapeutics. The unique space environment - characterized by microgravity and cosmic radiation - induces profound alterations in cancer cell behavior, immune responses, and tumor microenvironment (TME) interactions. These conditions offer a platform for studying cancer progression, enhancing drug discovery, and refining treatment strategies. This opinion article explores microgravity-induced changes in tumor biology, space-driven advancements in imaging and radiation research, and extraterrestrial contributions to cancer therapeutics. By leveraging these innovations, space research holds transformative potential for improving cancer diagnostics and treatment on Earth.</p>","PeriodicalId":23336,"journal":{"name":"Trends in cancer","volume":" ","pages":"433-440"},"PeriodicalIF":14.3000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in cancer","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.trecan.2025.02.003","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/12 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Space science is reshaping oncology by providing novel insights into cancer biology, diagnostics, and therapeutics. The unique space environment - characterized by microgravity and cosmic radiation - induces profound alterations in cancer cell behavior, immune responses, and tumor microenvironment (TME) interactions. These conditions offer a platform for studying cancer progression, enhancing drug discovery, and refining treatment strategies. This opinion article explores microgravity-induced changes in tumor biology, space-driven advancements in imaging and radiation research, and extraterrestrial contributions to cancer therapeutics. By leveraging these innovations, space research holds transformative potential for improving cancer diagnostics and treatment on Earth.
期刊介绍：
Trends in Cancer, a part of the Trends review journals, delivers concise and engaging expert commentary on key research topics and cutting-edge advances in cancer discovery and medicine.
Trends in Cancer serves as a unique platform for multidisciplinary information, fostering discussion and education for scientists, clinicians, policy makers, and patients & advocates.Covering various aspects, it presents opportunities, challenges, and impacts of basic, translational, and clinical findings, industry R&D, technology, innovation, ethics, and cancer policy and funding in an authoritative yet reader-friendly format.
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