Metagenomic Next-Generation Sequencing-Assisted Diagnosis of Japanese Spotted Fever: Report of One Case.

Q4 Medicine

中国医学科学院学报 Pub Date : 2025-02-01 DOI:10.3881/j.issn.1000-503X.15997

Ruan Yong-Chun, Zhou Yi-Qing, Zhang Hai-Wang, Zhou Jie, Duan Jin-Nan, Zhang Xiao-Jing, L I Ming-Hui

引用次数: 0

Abstract

Japanese spotted fever(JSF)is an infectious disease caused by Rickettsia japonica,with nonspecific clinical symptoms and a high risk of misdiagnosis.We reported a case of JSF,in which Rickettsia japonica was detected in blood cells by metagenomic next-generation sequencing.The patient recovered after treatment with doxycycline.This report provides a reference for the clinical diagnosis and treatment of JSF.

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元基因组下一代测序辅助诊断日本斑疹热：一个病例的报告

日本斑疹热（JSF）是一种由日本立克次体引起的传染性疾病，临床症状无特异性，误诊风险高。我们报告了一例JSF病例，其中通过新一代宏基因组测序在血细胞中检测到日本立克次体。患者经强力霉素治疗后痊愈。本报告为JSF的临床诊断和治疗提供参考。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

中国医学科学院学报 Medicine-Medicine (all)

CiteScore

0.60

自引率

0.00%

发文量

6813

期刊介绍： Acta Academiae Medicinae Sinicae was founded in February 1979. It is a comprehensive medical academic journal published in China and abroad, supervised by the Ministry of Health of the People's Republic of China and sponsored by the Chinese Academy of Medical Sciences and Peking Union Medical College. The journal mainly reports the latest research results, work progress and dynamics in the fields of basic medicine, clinical medicine, pharmacy, preventive medicine, biomedicine, medical teaching and research, aiming to promote the exchange of medical information and improve the academic level of medicine. At present, the journal has been included in 10 famous foreign retrieval systems and their databases [Medline (PubMed online version), Elsevier, EMBASE, CA, WPRIM, ExtraMED, IC, JST, UPD and EBSCO-ASP]; and has been included in important domestic retrieval systems and databases [China Science Citation Database (Documentation and Information Center of the Chinese Academy of Sciences), China Core Journals Overview (Peking University Library), China Science and Technology Paper Statistical Source Database (China Science and Technology Core Journals) (China Institute of Scientific and Technological Information), China Science and Technology Journal Paper and Citation Database (China Institute of Scientific and Technological Information)].