Paracoccidiomicosis: a case report

IF 2 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI:10.1016/j.oooo.2025.01.072

Maria Sofia Schreiber Peralta, Sofia Helena Llamosas Kriskovich, Clara Belen Sosa Legal, María Cristina Gómez Amarilla, Elisa Noemi Oviedo, Maria Eugenia Ayala Pereira, Maria Alejandra Portillo Martinez

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Abstract

Paracoccidiomycosis is a deep, chronic granulomatous systemic blastomycosis that spreads through blood and lymphatic circulation, affecting internal organs. A 65-year-old male patient is presented with pathognomonic signs and symptoms of mycosis, such as edema of the upper lip, ulcers with a moriform appearance throughout the oral mucosa with an addition of blackish dots and a productive cough, for 1 year evolution, to confirm the diagnosis an incisional biopsy of the upper lip was performed and sent for anatomopathological examination, the result was papillary hyperplasia with bacterial colonies, without fungal structures, due to the clinical characteristics the biopsy was repeated, with the final result of Paracoccidiomycosis. Is indicated an oral medication, Fluconazole 150 mg was used once a week for initial treatment and the patient was refered to a specialist for final treatment. This case demonstrates the importance of clinical diagnosis and its correlation with histology.

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副球孢子菌病是一种深部、慢性肉芽肿性全身性大疱性真菌病，通过血液和淋巴循环扩散，影响内脏器官。一名 65 岁的男性患者出现了真菌病的典型症状和体征，如上唇水肿、口腔粘膜上出现溃疡，溃疡呈蘑菇状，并伴有淡黑色小点，还伴有有痰咳嗽，病程长达 1 年、为了确诊，对上唇进行了切口活检，并送去进行解剖病理学检查，结果是乳头状增生，有细菌菌落，无真菌结构，由于临床特征，活检结果为副球孢子菌病。医生建议使用氟康唑 150 毫克口服药物进行初步治疗，每周一次，并将患者转诊至专科医生进行最终治疗。该病例说明了临床诊断及其与组织学相关性的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Oral Surgery Oral Medicine Oral Pathology Oral Radiology DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.80

自引率

6.90%

发文量

1217

审稿时长

2-4 weeks

期刊介绍： Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology is required reading for anyone in the fields of oral surgery, oral medicine, oral pathology, oral radiology or advanced general practice dentistry. It is the only major dental journal that provides a practical and complete overview of the medical and surgical techniques of dental practice in four areas. Topics covered include such current issues as dental implants, treatment of HIV-infected patients, and evaluation and treatment of TMJ disorders. The official publication for nine societies, the Journal is recommended for initial purchase in the Brandon Hill study, Selected List of Books and Journals for the Small Medical Library.