Bilateral mandibular juvenile ossifying trabecular fibroma in a pediatric patient: a case report of a rare entity

IF 2 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Oral Surgery Oral Medicine Oral Pathology Oral Radiology Pub Date : 2025-03-14 DOI:10.1016/j.oooo.2025.01.046

Maria Paula Novaes Camargo Manna, Yuri de Lima Medeiros, Lívia Marquesdos Santos, Zarife Tirapani Adum Resende, Priscila Faquini Macedo, Bruno Augusto Benevenuto de Andrade, Daniel Amaral Alves Marlière

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Abstract

The purpose of this study was to report a rare case of bilateral mandibular trabecular juvenile ossifying fibroma (TJOF) in a pediatric patient. A 13-year-old male patient presented to the dentist with swelling of the right face. Cone beam computed tomography revealed hypodense areas associated with hyperdense islands and expansion of the cortical bone in the bilateral posterior mandibles. An incisional biopsy was performed. Histologic analysis revealed irregular trabeculae of immature bone and calcified bone structures in a hypercellular stroma with spindle cells. The cells were immunopositive for the SATB2 marker and negative for AE1/AE3 cytokeratin. The final diagnosis was TJOF. Enucleation, curettage, and peripheral osteotomy using a rapid prototyping biomodel of the tumors were performed. At the 12-month follow-up, a left-sided recurrence was noted, and another surgical approach was performed. Postoperative tomographic images suggested appropriate healing at the 24-month follow-up, demonstrating complete removal of the tumor.

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小儿双侧青少年下颌骨骨化小梁纤维瘤1例：罕见病例报告

本研究的目的是报告一例罕见的双侧下颌小梁青少年骨化性纤维瘤（TJOF）的儿科患者。13岁男性患者右脸肿胀就诊。圆锥束计算机断层扫描显示双侧后下颌低密度区伴高密度岛和皮质骨扩张。行切口活检。组织学分析显示，在梭形细胞的高细胞间质中，未成熟骨有不规则的骨小梁和钙化的骨结构。细胞SATB2标记物免疫阳性，AE1/AE3细胞角蛋白阴性。最终诊断为TJOF。使用肿瘤的快速原型生物模型进行去核、刮除和周围截骨。在12个月的随访中，发现左侧复发，并进行了另一次手术。术后断层图像显示在24个月的随访中适当愈合，显示肿瘤完全切除。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Oral Surgery Oral Medicine Oral Pathology Oral Radiology DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.80

自引率

6.90%

发文量

1217

审稿时长

2-4 weeks

期刊介绍： Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology is required reading for anyone in the fields of oral surgery, oral medicine, oral pathology, oral radiology or advanced general practice dentistry. It is the only major dental journal that provides a practical and complete overview of the medical and surgical techniques of dental practice in four areas. Topics covered include such current issues as dental implants, treatment of HIV-infected patients, and evaluation and treatment of TMJ disorders. The official publication for nine societies, the Journal is recommended for initial purchase in the Brandon Hill study, Selected List of Books and Journals for the Small Medical Library.