Metastatic adenocarcinoma: a case report of multiple primary tumors in the oral cavity

IF 2 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE
Juliana Meneses Montalvão Costa, Liliana Wolf Braun, Thais Lins Soares Leite, Luis Afonso Tochetto, Marco Antonio Trevizani Martins, Vinicius Coelho Carrard, Manoela Domingues Martins
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引用次数: 0

Abstract

A 59-year-old male patient was referred to the oral medicine department because of persistent sialorrhea and dysphagia resulting from squamous cell carcinoma of the esophagus that was treated with radiotherapy in 2021. The patient was taking omeprazole 20 mg daily and denied smoking or alcohol consumption regularly. During evaluation, a hard asymptomatic nodule was identified on the right lateral border of the patient's tongue. An incisional biopsy revealed adenosquamous carcinoma, and the patient underwent partial glossectomy with supraomohyoid neck dissection. Two months later, the patient developed a hard submucosal nodule on the lower lip, which was diagnosed as conventional polymorphic adenocarcinoma. Metastatic lesions of polymorphic adenocarcinoma were also detected in the right temporal region, eyebrow, and upper and lower lips. Palliative chemotherapy was recommended, consisting of 8 cycles of carboplatin AUC 5 and paclitaxel 175 mg/m2 administered every 21 days, followed by the FOLFOX (leucovorin, fluorouracil, and oxaliplatin) second-line chemotherapy protocol.
转移性腺癌:口腔多发原发肿瘤1例报告
一名59岁男性患者因食管鳞状细胞癌导致的持续唾液和吞咽困难而被转介到口腔内科,该患者于2021年接受放疗。患者每日服用奥美拉唑20毫克,不吸烟、不饮酒。在评估过程中,在患者舌的右侧边缘发现了一个坚硬的无症状结节。切口活检显示腺鳞癌,患者接受部分舌骨切除术并肩胛舌骨上颈清扫术。2个月后,患者在下唇出现坚硬的粘膜下结节,诊断为常规多形态腺癌。在右侧颞区、眉毛、上下唇也发现了多态腺癌的转移灶。推荐姑息性化疗,包括8个周期的卡铂AUC 5和紫杉醇175 mg/m2,每21天给药,然后是FOLFOX(亚叶酸钙、氟尿嘧啶和奥沙利铂)二线化疗方案。
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来源期刊
Oral Surgery Oral Medicine Oral Pathology Oral Radiology
Oral Surgery Oral Medicine Oral Pathology Oral Radiology DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
3.80
自引率
6.90%
发文量
1217
审稿时长
2-4 weeks
期刊介绍: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology is required reading for anyone in the fields of oral surgery, oral medicine, oral pathology, oral radiology or advanced general practice dentistry. It is the only major dental journal that provides a practical and complete overview of the medical and surgical techniques of dental practice in four areas. Topics covered include such current issues as dental implants, treatment of HIV-infected patients, and evaluation and treatment of TMJ disorders. The official publication for nine societies, the Journal is recommended for initial purchase in the Brandon Hill study, Selected List of Books and Journals for the Small Medical Library.
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