The Medicinal Chemist’s Oath

Abstract

My med chem wish, my med chem dream: Fulfilling work, a thriving team. Identify receptor sites For drug design in silico, Dynamic dance in docking pose, Computer-aided modelling. High throughput screen, to short-list hit, Then hit-to-lead through synthesis: Furan, pyrrole, pyrimidine, Suzuki, Grignard, Finkelstein. To stand on shoulders of forebears, Upon whose stance, we build, advance, A drug-like lead to optimize: Lipinski’s five, a good logP, PK/PD to NCE, To candidate─pre-clinical. But in the end, it is for them, From bench to bed to humankind, For people with disease, despair, True face behind our molecules─ The reason why we chemists toil; To touch the face of humankind, Create the drugs that save the lives, My med chem goals, my med chem strives. This article has not yet been cited by other publications.