[Treatments de-escalation in rheumatoid arthritis].

Abstract

The number of rheumatoid arthritis patients in clinical remission has increased dramatically. We owe this progress to the advent of biotherapy in the 1990s, but also to a more focused therapeutic approach. Managing remission is therefore a contemporary challenge and raises many questions: Do biotherapies lead to a cure or to drug-induced remission? What are the chances of reducing or stopping treatment? What factors are associated with successful discontinuation? How and in what order to proceed when patients are taking several treatments at the same time? In this article, concrete, pragmatic answers based on the latest recommendations and current knowledge are provided.