Construction of Amidines via palladium-catalyzed three-component reaction of Arylacetylenes, t-Butylisonitrile and O-benzoyl Hydroxylamines

IF 1.5 4区化学 Q3 CHEMISTRY, ORGANIC

Tetrahedron Letters Pub Date : 2025-03-06 DOI:10.1016/j.tetlet.2025.155534

Jianquan Hong, Feng Zheng, Xiaoyu Wang, Mingyu Ma, Yupeng Yang, Lianguang Huo, Shuai Huang, Changge Zheng

引用次数: 0

Abstract

A palladium-catalyzed three-component reaction between arylacetylenes, t-butylisonitrile and O-benzoyl hydroxylamines has been developed. This transformation provides an efficient approach to access various alkynylamidine derivatives via tandem CH activation/insertion/amidination procedure.

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来源期刊

Tetrahedron Letters 化学-有机化学

CiteScore

3.50

自引率

5.60%

发文量

521

审稿时长

28 days

期刊介绍： Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.