Andrographolide and its Derivatives in Cardiovascular Disease: A Comprehensive Review.

IF 2.1 4区 医学 Q3 CHEMISTRY, MEDICINAL
Planta medica Pub Date : 2025-03-07 DOI:10.1055/a-2542-0756
Shenjie Zhang, Xiaokai Xie, Juan Zhao, Yilong Jiang, Chao Huang, Qi Li, Boyu Xia, Le Yin, Xiaomei Yuan, Qingsheng You
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引用次数: 0

Abstract

Cardiovascular disease is one of the main causes of mortality worldwide. Andrographolide represents an important category of natural phytochemicals that has significant therapeutic potential in various conditions such as acute lung injury, heart disease, and viral infections due to its anti-oxidative, anti-inflammatory, and anti-apoptotic properties. This compound plays a protective role in human pathophysiology. This review provides a comprehensive overview of the effects of andrographolide on cardiovascular disease and examines its essential roles and mechanisms in cardiovascular disease and other vascular dysfunctions. The data collected in this review serve as a comprehensive reference for the role of andrographolide in cardiovascular disease and provide valuable insights for further research and the development of andrographolide as a novel therapeutic approach for cardiovascular disease.

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来源期刊
Planta medica
Planta medica 医学-药学
CiteScore
5.10
自引率
3.70%
发文量
101
审稿时长
1.8 months
期刊介绍: Planta Medica is one of the leading international journals in the field of natural products – including marine organisms, fungi as well as micro-organisms – and medicinal plants. Planta Medica accepts original research papers, reviews, minireviews and perspectives from researchers worldwide. The journal publishes 18 issues per year. The following areas of medicinal plants and natural product research are covered: -Biological and Pharmacological Activities -Natural Product Chemistry & Analytical Studies -Pharmacokinetic Investigations -Formulation and Delivery Systems of Natural Products. The journal explicitly encourages the submission of chemically characterized extracts.
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