Kevin Qian, Björn Hanf, Prof. Christopher Cummins, Prof. Dorothea Fiedler
{"title":"Rücktitelbild: Monodisperse Chemical Oligophosphorylation of Peptides via Protected Oligophosphorimidazolide Reagents (Angew. Chem. 11/2025)","authors":"Kevin Qian, Björn Hanf, Prof. Christopher Cummins, Prof. Dorothea Fiedler","doi":"10.1002/ange.202502765","DOIUrl":null,"url":null,"abstract":"<p>Oligophosphorylated peptides were prepared by Kevin Qian, Björn Hanf, Christopher Cummins, and Dorothea Fiedler in their Research Article (e202419147). Oligophosphorimidazolide reagents are presented that enable the conjugation of multiple phosphates to phosphopeptides, yielding derivatives with monodisperse phosphate chain lengths. The picture illustrates different peptides with varying phosphate chain lengths, bearing either a terminal protecting group or a free oligophosphate moiety.\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure>\n </p>","PeriodicalId":7803,"journal":{"name":"Angewandte Chemie","volume":"137 11","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ange.202502765","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Angewandte Chemie","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/ange.202502765","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Oligophosphorylated peptides were prepared by Kevin Qian, Björn Hanf, Christopher Cummins, and Dorothea Fiedler in their Research Article (e202419147). Oligophosphorimidazolide reagents are presented that enable the conjugation of multiple phosphates to phosphopeptides, yielding derivatives with monodisperse phosphate chain lengths. The picture illustrates different peptides with varying phosphate chain lengths, bearing either a terminal protecting group or a free oligophosphate moiety.
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