E. F. Panarin, O. N. Zhuravskaya, A. V. Sitko, E. N. Vlasova, A. A. Shtro
{"title":"Copolymers of Acrylamides and Acrylic Acid with Antiviral Activity","authors":"E. F. Panarin, O. N. Zhuravskaya, A. V. Sitko, E. N. Vlasova, A. A. Shtro","doi":"10.1134/S1560090424601377","DOIUrl":null,"url":null,"abstract":"<p>Carboxylic polyelectrolytes, water-soluble copolymers of acrylic acid and <i>N</i>-substituted acrylamides, were synthesized for the first time by reactions in the chains of poly(acrylic anhydride) with aromatic amines. The structure, composition, and molecular weight characteristics of the copolymers were determined. The possibility of synthesizing alternating copolymers of acrylic acid was demonstrated. The copolymers of varying composition characterized by low cytotoxicity and activity against herpes simplex virus were prepared.</p>","PeriodicalId":739,"journal":{"name":"Polymer Science, Series B","volume":"66 4","pages":"556 - 560"},"PeriodicalIF":1.0000,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polymer Science, Series B","FirstCategoryId":"1","ListUrlMain":"https://link.springer.com/article/10.1134/S1560090424601377","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"POLYMER SCIENCE","Score":null,"Total":0}
引用次数: 0
Abstract
Carboxylic polyelectrolytes, water-soluble copolymers of acrylic acid and N-substituted acrylamides, were synthesized for the first time by reactions in the chains of poly(acrylic anhydride) with aromatic amines. The structure, composition, and molecular weight characteristics of the copolymers were determined. The possibility of synthesizing alternating copolymers of acrylic acid was demonstrated. The copolymers of varying composition characterized by low cytotoxicity and activity against herpes simplex virus were prepared.
期刊介绍:
Polymer Science, Series B is a journal published in collaboration with the Russian Academy of Sciences. Series B experimental and theoretical papers and reviews dealing with the synthesis, kinetics, catalysis, and chemical transformations of macromolecules, supramolecular structures, and polymer matrix-based composites (6 issues a year). All journal series present original papers and reviews covering all fundamental aspects of macromolecular science. Contributions should be of marked novelty and interest for a broad readership. Articles may be written in English or Russian regardless of country and nationality of authors. All manuscripts are peer reviewed