Spray-induced gene silencing for crop protection: recent advances and emerging trends.

IF 4.1 2区生物学 Q1 PLANT SCIENCES

Frontiers in Plant Science Pub Date : 2025-02-20 eCollection Date: 2025-01-01 DOI:10.3389/fpls.2025.1527944

Can Chen, Muhammad Imran, Xianyang Feng, Xihui Shen, Zhongke Sun

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引用次数: 0

Abstract

The RNA-based spray-induced gene silencing (SIGS) technology represents an ecologically sustainable approach to crop protection and pathogen management. Following the recent approval of Ledprona as the first sprayable double-stranded RNA (dsRNA) biopesticide by the EPA at the end of 2023, SIGS has emerged as a focal point in both academic and industrial sectors. This review analyzes recent advances and emerging trends in SIGS. The application of SIGS for crop protection, including the control of insects, fungal pathogens, and viruses, is briefly summarized. Distinguishing this review from others, we delve into practical aspects of the technology, such as the selection and screening of target genes, large-scale production methods, and delivery systems, highlighting major advancements in these areas and also addressing the remaining questions and issues, particularly concerning safety concerns and controlling harmful weeds. Finally, this review emphasizes the emerging trends in SIGS technology, particularly its integration with nanotechnology and other methodologies. Collectively, the rapid progress in SIGS studies is poised to accelerate the maturation and application of this technology.

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来源期刊

Frontiers in Plant Science PLANT SCIENCES-

CiteScore

7.30

自引率

14.30%

发文量

4844

审稿时长

14 weeks

期刊介绍： In an ever changing world, plant science is of the utmost importance for securing the future well-being of humankind. Plants provide oxygen, food, feed, fibers, and building materials. In addition, they are a diverse source of industrial and pharmaceutical chemicals. Plants are centrally important to the health of ecosystems, and their understanding is critical for learning how to manage and maintain a sustainable biosphere. Plant science is extremely interdisciplinary, reaching from agricultural science to paleobotany, and molecular physiology to ecology. It uses the latest developments in computer science, optics, molecular biology and genomics to address challenges in model systems, agricultural crops, and ecosystems. Plant science research inquires into the form, function, development, diversity, reproduction, evolution and uses of both higher and lower plants and their interactions with other organisms throughout the biosphere. Frontiers in Plant Science welcomes outstanding contributions in any field of plant science from basic to applied research, from organismal to molecular studies, from single plant analysis to studies of populations and whole ecosystems, and from molecular to biophysical to computational approaches. Frontiers in Plant Science publishes articles on the most outstanding discoveries across a wide research spectrum of Plant Science. The mission of Frontiers in Plant Science is to bring all relevant Plant Science areas together on a single platform.