[The role of meibum proteins in the pathogenesis of meibomian gland dysfunction].

Q3 Medicine

Vestnik oftalmologii Pub Date : 2025-01-01 DOI:10.17116/oftalma202514101170

T N Safonova, G V Zaitseva

引用次数: 0

Abstract

Proteins and lipids in the meibum help maintain the balanced chemical composition of the tear film. However, the secretion of the meibomian glands contains various protein fractions, the function and effects of which on the lipid profile remain incompletely understood. This literature review provides a description of the main proteins of the meibum and their roles in the pathogenesis of meibomian gland dysfunction associated with age-related changes and metabolic disorders that lead to impaired tear film functionality. The article also analyzes modern methods for studying meibomian gland secretion.

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[睑板蛋白在睑板腺功能障碍发病机制中的作用]。

细胞膜中的蛋白质和脂质有助于维持泪膜化学成分的平衡。然而，睑板腺的分泌含有各种蛋白质组分，其对脂质谱的功能和影响仍不完全清楚。本文综述了睑脂的主要蛋白及其在睑脂腺功能障碍发病机制中的作用，这些功能障碍与年龄相关的变化和代谢紊乱相关，导致泪膜功能受损。文章还分析了睑板腺分泌的现代研究方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Vestnik oftalmologii Medicine-Ophthalmology

CiteScore

0.80

自引率

0.00%

发文量

129

期刊介绍： The journal publishes materials on the diagnosis and treatment of eye diseases, hygiene of vision, prevention of ophthalmic affections, history of Russian ophthalmology, organization of ophthalmological aid to the population, as well as the problems of special equipment. Original scientific articles and surveys on urgent problems of theory and practice of Russian and foreign ophthalmology are published. The journal contains book reviews on ophthalmology, information on the activities of ophthalmologists" scientific societies, chronicle of congresses and conferences.The journal is intended for ophthalmologists and scientific workers dealing with clinical problems of diseases of the eye and physiology of vision.