Successful management of a pregnancy women with sudden onset of acute pancreatitis: A case report and literature review

IF 2 4区医学 Q2 OBSTETRICS & GYNECOLOGY

Taiwanese Journal of Obstetrics & Gynecology Pub Date : 2025-03-01 DOI:10.1016/j.tjog.2025.01.003

Yi-Er Huang , Chih-Yi Yang

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引用次数: 0

Abstract

Objective

Hypertriglyceridemia (HTG) is a rare cause of acute pancreatitis (AP) in pregnancies and has emerged as an aggravating factor of severe pancreatitis. To enhance the diagnosis and management of HTG-induced AP during pregnancy by improving early recognition, optimizing treatment strategies, and minimizing maternal and fetal complications.

Case Report

This is a 29-year-old multigravida woman at a gestational age of 34 weeks and 2 days who presented with sudden abdominal pain and vomiting. She had severe hypertriglyceridemia (7855 mg/dL) and was diagnosed with acute pancreatitis. After an emergency cesarean section, the patient received aggressive hydration, as well as fenofibrate and gemfibrozil as lipid-lowering agents, along with other supportive care. This treatment led to a successful recovery.

Conclusion

The management of HTG-induced AP must consider both maternal and fetal health, with options such as lipid-lowering agents and plasmapheresis being explored, further research was required to ascertain their safety during pregnancy.

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妊娠妇女突发性急性胰腺炎的成功治疗：1例报告并文献复习

目的高甘油三酯血症（HTG）是妊娠期急性胰腺炎（AP）的一种罕见病因，已成为严重胰腺炎的加重因素。通过提高早期识别，优化治疗策略，减少母胎并发症，提高htg诱导妊娠期AP的诊断和管理水平。病例报告：这是一名29岁多胎妇女，孕龄34周零2天，表现为突然腹痛和呕吐。她有严重的高甘油三酯血症（7855 mg/dL），诊断为急性胰腺炎。在紧急剖宫产手术后，患者接受了积极的水合治疗，同时服用非诺贝特和吉非罗齐作为降脂剂，以及其他支持性治疗。这种治疗使她成功康复。结论htg诱导AP的处理必须兼顾母婴健康，可考虑使用降脂剂和血浆置换等治疗方案，但需进一步研究其在妊娠期的安全性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Taiwanese Journal of Obstetrics & Gynecology OBSTETRICS & GYNECOLOGY-

CiteScore

3.60

自引率

23.80%

发文量

207

审稿时长

4-8 weeks

期刊介绍： Taiwanese Journal of Obstetrics and Gynecology is a peer-reviewed journal and open access publishing editorials, reviews, original articles, short communications, case reports, research letters, correspondence and letters to the editor in the field of obstetrics and gynecology. The aims of the journal are to: 1.Publish cutting-edge, innovative and topical research that addresses screening, diagnosis, management and care in women''s health 2.Deliver evidence-based information 3.Promote the sharing of clinical experience 4.Address women-related health promotion The journal provides comprehensive coverage of topics in obstetrics & gynecology and women''s health including maternal-fetal medicine, reproductive endocrinology/infertility, and gynecologic oncology. Taiwan Association of Obstetrics and Gynecology.