{"title":"[Disseminated intravascular coagulation caused by exertional heat stroke: a case report and literature review].","authors":"L Zhang, Z H Zhang, Z Y Sun, X Y Xu, G S Zhou","doi":"10.3760/cma.j.cn121090-20241225-00588","DOIUrl":null,"url":null,"abstract":"<p><p><b>Objective:</b> To explore the mechanisms and clinical manifestations of disseminated intravascular coagulation (DIC) caused by exertional heat stroke. <b>Methods:</b> Analyze the clinical data of a patient with exertional heat stroke in Yichang Central People's Hospital and review relevant literature to evaluate the association between heat stroke and DIC, summarizing clinical presentations and laboratory findings. <b>Results:</b> The patient exhibited symptoms such as high fever and altered consciousness after engaging in intense labor in a high-temperature environment. Laboratory tests showed a platelet count of 43×10(9)/L, D-dimer level of 5.3 mg/L, and prothrombin time of 21.8 s, which are consistent with a diagnosis of DIC. Following prompt cooling, fluid resuscitation, appropriate anticoagulant, goal-directed replacement therapy and supportive therapy, the patient's condition gradually improved. <b>Conclusion:</b> Exertional heat stroke can lead to DIC, and clinical attention should be paid to its early recognition and intervention. Effective coagulation management and timely anticoagulant and supportive therapy are crucial for improving prognosis.</p>","PeriodicalId":24016,"journal":{"name":"Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi","volume":"45 S1","pages":"68-72"},"PeriodicalIF":0.0000,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3760/cma.j.cn121090-20241225-00588","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: To explore the mechanisms and clinical manifestations of disseminated intravascular coagulation (DIC) caused by exertional heat stroke. Methods: Analyze the clinical data of a patient with exertional heat stroke in Yichang Central People's Hospital and review relevant literature to evaluate the association between heat stroke and DIC, summarizing clinical presentations and laboratory findings. Results: The patient exhibited symptoms such as high fever and altered consciousness after engaging in intense labor in a high-temperature environment. Laboratory tests showed a platelet count of 43×10(9)/L, D-dimer level of 5.3 mg/L, and prothrombin time of 21.8 s, which are consistent with a diagnosis of DIC. Following prompt cooling, fluid resuscitation, appropriate anticoagulant, goal-directed replacement therapy and supportive therapy, the patient's condition gradually improved. Conclusion: Exertional heat stroke can lead to DIC, and clinical attention should be paid to its early recognition and intervention. Effective coagulation management and timely anticoagulant and supportive therapy are crucial for improving prognosis.