Midface Toddler Excoriation Syndrome (MiTES): A Review.

IF 1.2 4区医学 Q3 DERMATOLOGY

Pediatric Dermatology Pub Date : 2025-03-03 DOI:10.1111/pde.15917

Varniraj Patel, Deepika Yadav, Maitri Patel, Vaishnavi Modi, Krishna Deb Barman, Vishal Gaurav

引用次数: 0

Abstract

Midface toddler excoriation syndrome (MiTES) is a rare dermatological condition characterized by chronic, self-inflicted excoriations of the midface, often leading to significant scarring and hyperpigmentation. It typically affects young children, with a male predominance. MiTES is linked to genetic mutations in the PRDM12 gene. Treatment approaches vary, including topical antimicrobials, emollients, steroids, and oral medications aimed at reducing scratching impulses. However, responses are inconsistent, and many patients show only partial or moderate improvement. This review consolidates current knowledge of MiTES, emphasizing its clinical features, genetic basis, and management strategies.

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中面部幼儿割礼综合征（MiTES）是一种罕见的皮肤病，其特征是中面部的慢性自伤性割礼，通常会导致明显的瘢痕和色素沉着。该病通常发生在幼儿身上，男性居多。MiTES 与 PRDM12 基因的遗传突变有关。治疗方法多种多样，包括外用抗菌药、润肤剂、类固醇激素和旨在减少搔抓冲动的口服药物。然而，治疗效果并不一致，许多患者仅有部分或轻度改善。这篇综述综合了目前对 MiTES 的了解，强调了其临床特征、遗传基础和治疗策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pediatric Dermatology 医学-皮肤病学

CiteScore

3.20

自引率

6.70%

发文量

269

审稿时长

1 months

期刊介绍： Pediatric Dermatology answers the need for new ideas and strategies for today''s pediatrician or dermatologist. As a teaching vehicle, the Journal is still unsurpassed and it will continue to present the latest on topics such as hemangiomas, atopic dermatitis, rare and unusual presentations of childhood diseases, neonatal medicine, and therapeutic advances. As important progress is made in any area involving infants and children, Pediatric Dermatology is there to publish the findings.