{"title":"Surface Functionalization of Elastomers with Biopolymers.","authors":"Emilie Morin, Elana Muzzy, Andrea S Carlini","doi":"10.1007/978-1-0716-4402-7_13","DOIUrl":null,"url":null,"abstract":"<p><p>Biopolymer coatings on elastomeric surfaces have significant impact for advancements in biomedicine as they combine flexible devices with complex biological functionality. Biopolymers offer increased ability for antimicrobial coatings, sensing of relevant biological markers, and controlled drug delivery. The methodologies available to conjugate these important biopolymers to flexible elastomeric substrates are vast and rapidly evolving. This chapter aims to compile methodologies across the application space of biopolymer conjugation to elastomers. We present a guide to the field and methods ranging from surface activation and functionalization, grafting-to and grafting-from of biopolymers, and characterization of the resulting substrates.</p>","PeriodicalId":18490,"journal":{"name":"Methods in molecular biology","volume":"2902 ","pages":"197-227"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Methods in molecular biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/978-1-0716-4402-7_13","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Biochemistry, Genetics and Molecular Biology","Score":null,"Total":0}
引用次数: 0
Abstract
Biopolymer coatings on elastomeric surfaces have significant impact for advancements in biomedicine as they combine flexible devices with complex biological functionality. Biopolymers offer increased ability for antimicrobial coatings, sensing of relevant biological markers, and controlled drug delivery. The methodologies available to conjugate these important biopolymers to flexible elastomeric substrates are vast and rapidly evolving. This chapter aims to compile methodologies across the application space of biopolymer conjugation to elastomers. We present a guide to the field and methods ranging from surface activation and functionalization, grafting-to and grafting-from of biopolymers, and characterization of the resulting substrates.
期刊介绍:
For over 20 years, biological scientists have come to rely on the research protocols and methodologies in the critically acclaimed Methods in Molecular Biology series. The series was the first to introduce the step-by-step protocols approach that has become the standard in all biomedical protocol publishing. Each protocol is provided in readily-reproducible step-by-step fashion, opening with an introductory overview, a list of the materials and reagents needed to complete the experiment, and followed by a detailed procedure that is supported with a helpful notes section offering tips and tricks of the trade as well as troubleshooting advice.