Ferroptosis in adipose tissue: A promising pathway for treating obesity?

IF 27.7 1区生物学 Q1 CELL BIOLOGY

Cell metabolism Pub Date : 2025-03-04 DOI:10.1016/j.cmet.2025.01.029

John R. Speakman

引用次数: 0

Abstract

Using a high-fat-diet (HFD) mouse model and clinical samples, Wang et al.¹ in this issue of Cell Metabolism report that ferroptotic signaling is involved in the expansion of adipose tissue and promotes adaptive thermogenesis in beige adipocytes. This finding may represent a promising new avenue for treating obesity.

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脂肪组织中的铁下垂：治疗肥胖的一个有希望的途径？

Wang等人利用高脂饮食（HFD）小鼠模型和临床样本1在本期《细胞代谢》杂志上报道，铁致凋亡信号参与脂肪组织的扩张，并促进米色脂肪细胞的适应性产热。这一发现可能为治疗肥胖提供了一条有希望的新途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cell metabolism 生物-内分泌学与代谢

CiteScore

48.60

自引率

1.40%

发文量

173

审稿时长

2.5 months

期刊介绍： Cell Metabolism is a top research journal established in 2005 that focuses on publishing original and impactful papers in the field of metabolic research.It covers a wide range of topics including diabetes, obesity, cardiovascular biology, aging and stress responses, circadian biology, and many others. Cell Metabolism aims to contribute to the advancement of metabolic research by providing a platform for the publication and dissemination of high-quality research and thought-provoking articles.