{"title":"Renal Osteodystrophy in 2 Canine Patients.","authors":"Erez Cohen-Mivtach","doi":"10.1177/08987564251324114","DOIUrl":null,"url":null,"abstract":"<p><p>This report presents 2 cases of renal osteodystrophy in young to middle-aged dogs, emphasizing the clinical presentation, diagnostic challenges, and therapeutic management. Both cases exhibited similar symptoms including oral abnormalities and renal dysfunction, with radiographic evidence revealing substantial bone resorption in the mandibles and maxillae. Histological analysis post-mortem confirmed advanced chronic kidney disease characterized by extensive fibrosis and glomerular abnormalities. The report underscores the critical importance of early detection of chronic kidney disease to mitigate the development of secondary hyperparathyroidism and subsequent renal osteodystrophy. These cases illustrate the complexities of diagnosing and managing renal osteodystrophy in dogs, highlighting the need for comprehensive diagnostic approaches combining clinical evaluation, radiographic imaging, and histopathological examination. Effective management strategies discussed include dietary modification, phosphate binding agents, and supportive care to alleviate clinical symptoms and slow progression of disease. The outcomes underscore the grave prognosis associated with advanced stages of chronic kidney disease and emphasize the significance of proactive screening and early intervention in mitigating renal osteodystrophy in canine patients.</p>","PeriodicalId":17584,"journal":{"name":"Journal of Veterinary Dentistry","volume":" ","pages":"8987564251324114"},"PeriodicalIF":0.7000,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Veterinary Dentistry","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1177/08987564251324114","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
This report presents 2 cases of renal osteodystrophy in young to middle-aged dogs, emphasizing the clinical presentation, diagnostic challenges, and therapeutic management. Both cases exhibited similar symptoms including oral abnormalities and renal dysfunction, with radiographic evidence revealing substantial bone resorption in the mandibles and maxillae. Histological analysis post-mortem confirmed advanced chronic kidney disease characterized by extensive fibrosis and glomerular abnormalities. The report underscores the critical importance of early detection of chronic kidney disease to mitigate the development of secondary hyperparathyroidism and subsequent renal osteodystrophy. These cases illustrate the complexities of diagnosing and managing renal osteodystrophy in dogs, highlighting the need for comprehensive diagnostic approaches combining clinical evaluation, radiographic imaging, and histopathological examination. Effective management strategies discussed include dietary modification, phosphate binding agents, and supportive care to alleviate clinical symptoms and slow progression of disease. The outcomes underscore the grave prognosis associated with advanced stages of chronic kidney disease and emphasize the significance of proactive screening and early intervention in mitigating renal osteodystrophy in canine patients.
期刊介绍:
The Journal of Veterinary Dentistry (JOVD) is the official peer-reviewed publication of the Foundation for Veterinary Dentistry. The JOVD provides a continuing education forum for veterinary dental scientists, veterinarians, dentists, and veterinary/dental technicians and hygienists who are engaged in veterinary dental practice. JOVD articles provide practical and scientifically sound information covering not only the medical and surgical aspects, but also specific categories as they relate to clinical practice.