Valuing health-related quality of life: an EQ-5D-5L value set for Morocco.

IF 3.3 3区医学 Q1 HEALTH CARE SCIENCES & SERVICES

Quality of Life Research Pub Date : 2025-06-01 Epub Date: 2025-02-28 DOI:10.1007/s11136-025-03930-1

Asmaa Azizi, Amal Boutib, Doha Achak, Fredrick Dermawan Purba, Fanni Rencz, Elmadani Saad, Abderraouf Hilali, Samir Ahid, Chakib Nejjari, Elly A Stolk, Bram Roudijk, Ibtissam Youlyouz-Marfak, Abdelghafour Marfak

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引用次数: 0

Abstract

Purpose: There is a growing interest in Health Technology Assessment (HTA) in Morocco. A national EQ-5D-5L value set would allow for the computation of Quality Adjusted Life Years (QALYs) in economic evaluations of healthcare interventions to support decision-making. This study aimed to develop a Moroccan EQ-5D-5L value set based on data from a representative sample of the Moroccan adult general population.

Methods: A Moroccan representative sample of adults was recruited using stratified quota sampling based on gender, age category, and place of residence. Data were collected between November 2022 and December 2023 using the international EuroQol valuation protocol, EQ-VT version 2.6.1. This protocol includes two elicitation techniques: the composite time trade-off (cTTO) and the discrete choice experiment (DCE). cTTO and DCE data were modeled using a heteroskedastic Tobit model and a conditional logit model, respectively. In addition, these models were combined using a hybrid model.

Results: A total of 976 respondents were included in the final analysis. The hybrid heteroskedastic model was considered the preferred model. The predicted utility values ranged from -1.492 for the worst health state (55555) to 1 for full health (11111), where the two mildest impaired states (11211 and 21111) had a utility value of 0.979. Pain/discomfort had the largest effect on health utility values, followed by anxiety/depression, mobility, self-care and usual activities.

Conclusion: Morocco is the third country in the Middle East and North Africa (MENA) region with an EQ-5D-5L value set. This study supports the use of EQ-5D-5L data for healthcare decision-making in the Moroccan context.

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评价与健康有关的生活质量：为摩洛哥设定的EQ-5D-5L值。

目的：摩洛哥对卫生技术评估（HTA）的兴趣日益浓厚。国家EQ-5D-5L值集将允许在医疗保健干预措施的经济评估中计算质量调整生命年（QALYs），以支持决策。本研究旨在根据摩洛哥成人一般人群的代表性样本数据开发摩洛哥EQ-5D-5L值集。方法：采用基于性别、年龄类别和居住地的分层配额抽样方法，招募具有代表性的摩洛哥成年人样本。数据收集于2022年11月至2023年12月，使用国际EuroQol评估协议EQ-VT版本2.6.1。该方案包括两种激发技术：复合时间权衡（cTTO）和离散选择实验（DCE）。cTTO和DCE数据分别使用异方差Tobit模型和条件logit模型建模。此外，使用混合模型将这些模型组合起来。结果：最终分析共纳入976名调查对象。混合异方差模型被认为是首选模型。预测的效用值范围从最差健康状态（55555）的-1.492到完全健康状态（11111）的1，其中两个最轻微受损状态（11211和21111）的效用值为0.979。疼痛/不适对健康效用价值的影响最大，其次是焦虑/抑郁、行动能力、自我保健和日常活动。结论：摩洛哥是中东北非（MENA）地区第三个拥有EQ-5D-5L值集的国家。本研究支持在摩洛哥背景下使用EQ-5D-5L数据进行医疗保健决策。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Quality of Life Research 医学-公共卫生、环境卫生与职业卫生

CiteScore

6.50

自引率

8.60%

发文量

224

审稿时长

3-8 weeks

期刊介绍： Quality of Life Research is an international, multidisciplinary journal devoted to the rapid communication of original research, theoretical articles and methodological reports related to the field of quality of life, in all the health sciences. The journal also offers editorials, literature, book and software reviews, correspondence and abstracts of conferences. Quality of life has become a prominent issue in biometry, philosophy, social science, clinical medicine, health services and outcomes research. The journal''s scope reflects the wide application of quality of life assessment and research in the biological and social sciences. All original work is subject to peer review for originality, scientific quality and relevance to a broad readership. This is an official journal of the International Society of Quality of Life Research.