Secondary Intention healing time of postoperative surgical cancer skin wounds with a biosynthetic porcine type i collagen dressing: A 306-patient retrospective, observational study.

IF 3.8 Q1 DERMATOLOGY

Actas dermo-sifiliograficas Pub Date : 2025-02-25 DOI:10.1016/j.ad.2025.02.022

A Gavillero-Martín, M Juliá-Roca, I Serra-Guillén, A Rodríguez-Hernández, E Manrique-Silva, A E López-Sundh, E Nagore

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引用次数: 0

Abstract

Background: Biosynthetic porcine type I collagen dressing is useful to close ulcers and secondary intention healing of surgical cancer wounds.

Objective: To identify factors associated with the healing time of such wounds.

Methods: We conducted a retrospective observational study of patients on oncological dermatological surgery in a cancer center. Healing time was studied based on age, sex, personal history of comorbidities, usual medication, anatomical location, type of surgery performed and size of the defect. Statistical analysis was performed using the ANOVA test and logistic regression.

Results: A total of 306 patients were included with a median age of 73 years (62.4%, men). The statistically significantly characteristics associated with a healing time≤66 days were location-auricle, nose, inner canthus, hand, retroauricular region and nail bed-use of the Mohs technique and defect sizes≤5.28cm².

Limitations: This is a retrospective study from a single center.

Conclusion: The use of biosynthetic porcine type I collagen dressings for the definitive closure of dermatological surgical cancer wounds seems particularly suitable for small defects of the inner canthus of the eye, hand, auricle, nose, forehead, retroauricular region, and nail bed.

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背景：生物合成猪 I 型胶原敷料可用于闭合溃疡和外科癌症伤口的二次意向愈合：确定与此类伤口愈合时间相关的因素：我们对一家癌症中心的皮肤科肿瘤手术患者进行了一项回顾性观察研究。根据年龄、性别、个人合并症病史、常用药物、解剖位置、手术类型和缺损大小对愈合时间进行了研究。统计分析采用方差分析和逻辑回归法：共纳入 306 名患者，中位年龄为 73 岁（62.4% 为男性）。从统计学角度看，与愈合时间≤66天相关的特征是位置--耳廓、鼻、内眦、手、耳后区域和甲床--莫氏技术的使用和缺损面积≤5.28平方厘米：局限性：这是一项来自单一中心的回顾性研究：结论：使用生物合成猪 I 型胶原蛋白敷料用于皮肤外科癌症伤口的最终闭合，似乎特别适用于眼眶内侧、手部、耳廓、鼻部、前额、耳后区域和甲床的小缺损。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Actas dermo-sifiliograficas DERMATOLOGY-

CiteScore

1.90

自引率

9.40%

发文量

473

审稿时长

56 weeks

期刊介绍： Actas Dermo-Sifiliográficas, publicación Oficial de la Academia Española de Dermatología y Venereología, es una revista de prestigio consolidado. Creada en 1909, es la revista mensual más antigua editada en España.En 2006 entró en Medline, y hoy resulta imprescindible para estar al día sobre la dermatología española y mundial.