{"title":"Hypokalemic periodic paralysis, a rare yet critical condition: A case report.","authors":"Saime Paydas, Mehmet Ali Gergerli, Ahmet Celik","doi":"10.3892/mi.2025.220","DOIUrl":null,"url":null,"abstract":"<p><p>Hypokalemic periodic paralysis (HPP) is a rare disease. Due to channelopathy caused by mutations in skeletal muscle ion channels, episodes of sudden flaccid muscle weakness and hypokalemia develop as a result of various trigger factors. The present study reports the case of a 25-year-old male patient with HPP admitted with acute onset numbness and paralysis in the extremities accompanying hypokalemia (2.66 mEq/l). The patient became asymptomatic following treatment with a potassium (K) supplement and was diagnosed with HPP. The present study describes this case of HPP in an aim to remind colleagues of the possibility of HPP in hypokalemic patients with muscle weakness and flaccid paralysis.</p>","PeriodicalId":74161,"journal":{"name":"Medicine international","volume":"5 2","pages":"21"},"PeriodicalIF":0.0000,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863296/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicine international","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3892/mi.2025.220","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Hypokalemic periodic paralysis (HPP) is a rare disease. Due to channelopathy caused by mutations in skeletal muscle ion channels, episodes of sudden flaccid muscle weakness and hypokalemia develop as a result of various trigger factors. The present study reports the case of a 25-year-old male patient with HPP admitted with acute onset numbness and paralysis in the extremities accompanying hypokalemia (2.66 mEq/l). The patient became asymptomatic following treatment with a potassium (K) supplement and was diagnosed with HPP. The present study describes this case of HPP in an aim to remind colleagues of the possibility of HPP in hypokalemic patients with muscle weakness and flaccid paralysis.