Sha Zhao, Xiuli Wu, Zhengtao Xu, Songyan Ye, Xingxing Wu
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引用次数: 0
Abstract
Transforming alkane C−H bonds into carbon-carbon and carbon-heteroatom bonds represents a paramount objective in synthetic chemistry with significant implications for sustainable production. Although transition-metal catalysts such as Pd, Rh etc have dominated this field, recent breakthroughs in metal-free approaches leveraging small-molecule catalysts or photogenerated intermediates have emerged as efficient and sustainable alternatives. These approaches facilitate precise C−H bond activation and selective formation of C−X (e. g., C, halogen, N, O) bonds under mild conditions, thereby paving a promising avenue for eco-friendly alkane transformations. This review provides an overview of recent advancements in homogeneous metal-free alkane functionalization, focusing on organocatalytic and photoinduced strategies, with the aim of enhancing mechanistic understanding and inspiring the development of innovative synthetic methodologies for the conversion of alkanes into high-value compounds.
期刊介绍：
The Chemical Record (TCR) is a "highlights" journal publishing timely and critical overviews of new developments at the cutting edge of chemistry of interest to a wide audience of chemists (2013 journal impact factor: 5.577). The scope of published reviews includes all areas related to physical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, polymer chemistry, materials chemistry, bioorganic chemistry, biochemistry, biotechnology and medicinal chemistry as well as interdisciplinary fields.
TCR provides carefully selected highlight papers by leading researchers that introduce the author''s own experimental and theoretical results in a framework designed to establish perspectives with earlier and contemporary work and provide a critical review of the present state of the subject. The articles are intended to present concise evaluations of current trends in chemistry research to help chemists gain useful insights into fields outside their specialization and provide experts with summaries of recent key developments.
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