A transition-metal-free 1,10-phenanthroline-promoted homocoupling reaction for the construction of biaryl diamides

IF 2.1 3区化学 Q2 CHEMISTRY, ORGANIC

Tetrahedron Pub Date : 2025-02-25 DOI:10.1016/j.tet.2025.134562

Shengxing Xie, Jinxia Yang, Rong Ma, Minghui Liu, Xinyuan Zhang, Neng-Fei Wang, Chengyu Wang, Lingkai Kong

引用次数: 0

Abstract

An efficient transition-metal-free 1,10-phenanthroline-promoted homocoupling reaction has been developed to construct biaryl diamides from 2-iodobenzamides. Various desired products were smoothly synthesized with readily available starting materials in good to excellent yields under the standard reaction conditions. And this method showed a wide substrate scope and good functional group tolerance.

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来源期刊

Tetrahedron 化学-有机化学

CiteScore

3.90

自引率

4.80%

发文量

439

审稿时长

34 days

期刊介绍： Tetrahedron publishes full accounts of research having outstanding significance in the broad field of organic chemistry and its related disciplines, such as organic materials and bio-organic chemistry. Regular papers in Tetrahedron are expected to represent detailed accounts of an original study having substantially greater scope and details than that found in a communication, as published in Tetrahedron Letters. Tetrahedron also publishes thematic collections of papers as special issues and ''Reports'', commissioned in-depth reviews providing a comprehensive overview of a research area.