Photosensitive lichenoid reaction accompanied by nonphotosensitive subacute prurigo caused by carbamazepine.

Photo-dermatology Pub Date : 1988-10-01
S Yasuda, N Mizuno, Y Kawabe, S Sakakibara
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Abstract

A 58-year-old man developed a lichenoid reaction on light-exposed areas and subacute prurigo separate from the sun-exposed areas after receiving 200 mg of carbamazepine daily for one year. The difference action spectrum for erythema with or without ingesting the drug ranged from 250 to 390 nm with peaks at 260 and 290 nm. A positive photoingestion test was obtained after administering 2 mg of carbamazepine orally in one dose. Patch test with carbamazepine was negative, while photopatch test with carbamazepine was positive. Positive intracutaneous test was obtained with an irradiated mixture of human serum albumin and carbamazepine at 24 h and 48 h after injection. This patient appeared to be a case of photosensitive lichenoid reaction accompanied by nonphotosensitive subacute prurigo caused by carbamazepine.

卡马西平引起的光敏性地衣样物质反应伴非光敏性亚急性痒疹。
一名58岁男子在每日服用200毫克卡马西平一年后,在暴露于光区的地衣样物质反应和亚急性瘙痒症。服用或不服用该药物对红斑的作用谱差异范围为250 ~ 390 nm,峰值为260和290 nm。口服卡马西平2 mg一次后,光摄取试验呈阳性。卡马西平斑贴试验阴性,卡马西平光贴试验阳性。用人血清白蛋白与卡马西平的混合物照射后,于注射后24 h和48 h皮内试验均呈阳性。本病例为卡马西平引起的光敏性地衣样物质反应伴非光敏性亚急性痒疹的病例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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