Isolated Atrial Amyloidosis in a Patient with Aortic Regurgitation and Paroxysmal Atrial Fibrillation.

IF 1.1 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

Internal Medicine Pub Date : 2025-09-01 Epub Date: 2025-02-22 DOI:10.2169/internalmedicine.5049-24

Hiroaki Kawano, Nozomi Ueki, Akira Senoo, Ichiro Matsumaru, Chikara Ohno, Tsuyoshi Yoshimuta, Takashi Miura, Mitsuaki Ueda, Takashi Kudo, Masahiro Nakashima, Koji Maemura

引用次数: 0

Abstract

A 65-year-old woman was admitted to our hospital with heart failure secondary to aortic regurgitation and paroxysmal atrial fibrillation (AF). During surgery for valve-sparing aortic root replacement, a biopsy was obtained from the right atrium because of paroxysmal AF and mild left ventricular hypokinesis. A histopathological examination revealed atrial natriuretic peptide amyloidosis, and the patient was clinically diagnosed with isolated atrial amyloidosis (IAA). Although IAA is rarely diagnosed clinically, it should be considered in patients with AF and heart failure.

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一名主动脉瓣反流和阵发性心房颤动患者的孤立性心房淀粉样变性。

一位65岁的女性因主动脉瓣反流和阵发性心房颤动导致心力衰竭入院。在保留瓣膜的主动脉根置换术中，由于阵发性心房颤动和轻度左室运动不足，对右心房进行了活检。组织病理学检查示心房利钠肽淀粉样变性，临床诊断为孤立性心房淀粉样变性（IAA）。虽然临床上很少诊断出IAA，但在房颤和心力衰竭患者中应考虑IAA。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Internal Medicine 医学-医学：内科

CiteScore

1.90

自引率

8.30%

发文量

审稿时长

2.2 months

期刊介绍： Internal Medicine is an open-access online only journal published monthly by the Japanese Society of Internal Medicine. Articles must be prepared in accordance with "The Uniform Requirements for Manuscripts Submitted to Biomedical Journals (see Annals of Internal Medicine 108: 258-265, 1988), must be contributed solely to the Internal Medicine, and become the property of the Japanese Society of Internal Medicine. Statements contained therein are the responsibility of the author(s). The Society reserves copyright and renewal on all published material and such material may not be reproduced in any form without the written permission of the Society.