Treatments for Recurrent Aphthous Stomatitis: A Literature Review.

IF 2.5 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Dentistry Journal Pub Date : 2025-01-31 DOI:10.3390/dj13020066

Maurizio D'Amario, Giordano Foffo, Filippo Grilli, Mario Capogreco, Tommaso Pizzolante, Sofia Rastelli

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引用次数: 0

Abstract

Background/objectives: This literature review aims to provide guidance on the treatment of recurrent aphthous stomatitis (RAS) based on studies published over the past 10 years.

Methods: This study included randomized clinical trials involving human patients from 2013 and 2023, published in any language. The trials examined both pharmacological and non-pharmacological treatments for aphthous lesions, mainly focusing on the adult population, with pain management as the primary outcome. The research was conducted using PubMed, EMBASE, and CINHAL databases.

Results: Most of the 45 analyzed studies focused on non-pharmacological therapies, which led to positive results with minimal adverse effects or contraindications, even when compared to cortisone-based treatments. Laser therapy also showed excellent results, particularly in the immediate post-treatment period. Non-pharmacological therapies appeared to offer the best risk-benefit ratio for patients suffering from RAS.

Conclusions: Treatment should be individualized based on the patient's specific form of RAS, and laser therapy can be used either as a standalone treatment or as an adjunct to other treatments considered in the review.

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来源期刊

Dentistry Journal Dentistry-Dentistry (all)

CiteScore

3.70

自引率

7.70%

发文量

213

审稿时长

11 weeks