{"title":"The Impact of STR Mutations on Kinship Identification.","authors":"Jing Liu, Zheng Wang, Yi-Ping Hou, Lin-Chuan Liao","doi":"10.12116/j.issn.1004-5619.2024.541008","DOIUrl":null,"url":null,"abstract":"<p><p>Kinship identification is an important field of forensic genetics research, which can be widely applied in inheritance disputes, criminal investigations, and the identification of victims in major disaster cases. At present, capillary electrophoresis-based STR analysis is still the main method for kinship identification, but the impact of STR mutations on kinship identification needs further exploration. This paper reviews the theoretical basis and research status at home and abroad of kinship identification. The challenge of STR mutation impact on kinship identification is prospected, and possible solutions are discussed in order to obtain a regular understanding of the impact of STR mutation on kinship identification and improve the accuracy of kinship analysis.</p>","PeriodicalId":12317,"journal":{"name":"法医学杂志","volume":"40 5","pages":"484-491"},"PeriodicalIF":0.0000,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"法医学杂志","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.12116/j.issn.1004-5619.2024.541008","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Kinship identification is an important field of forensic genetics research, which can be widely applied in inheritance disputes, criminal investigations, and the identification of victims in major disaster cases. At present, capillary electrophoresis-based STR analysis is still the main method for kinship identification, but the impact of STR mutations on kinship identification needs further exploration. This paper reviews the theoretical basis and research status at home and abroad of kinship identification. The challenge of STR mutation impact on kinship identification is prospected, and possible solutions are discussed in order to obtain a regular understanding of the impact of STR mutation on kinship identification and improve the accuracy of kinship analysis.