Two New Aromatic Sesquiterpenes from Tobacco Flower Extract and Their Antibacterial Activity

IF 0.8 4区 化学 Q4 CHEMISTRY, MEDICINAL
Xin-Yao Huang, Jin-Yun Liu, Jin Wang, Li-Ying Yang, Chong-Jun Xu, Kua-Ping Wang, Guang-Yu Yang, Qiu-Fen Hu, Shi-Tao Xu, Hua-Yin Liu
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引用次数: 0

Abstract

Two new aromatic sesquiterpenes, nicosesquites C and D (1 and 2), as well as five known sesquiterpenes (3–7), were isolated from tobacco flower extract. Their structures were determined mainly by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds 1 and 2 were tested for their antibacterial activity against five pathogenic strains (Staphylococcus aureus, Escherichia coli, Streptococcus pyogenes, Bacillus subtilis, and Proteus spp.). The results revealed that both compounds showed high antibacterial activity with bacteriostatic diameters in the range of 18.2 ± 1.4~25.8 ± 2.2 mm, respectively. In addition, compounds 1 and 2 also have a weak resin-like aroma, and they have potential value for use as an essence for cigarettes.

Abstract Image

烟草花提取物中两种新的芳香倍半萜及其抑菌活性
从烟草花提取物中分离到两个新的芳香倍半萜,nicosesquites C和D(1和2),以及5个已知的倍半萜(3-7)。它们的结构主要通过光谱方法确定,包括广泛的一维和二维核磁共振技术。化合物1和2对5种病原菌(金黄色葡萄球菌、大肠杆菌、化脓性链球菌、枯草芽孢杆菌和变形杆菌)的抑菌活性进行了测试。结果表明,两种化合物均具有较高的抑菌活性,抑菌直径范围分别为18.2±1.4~25.8±2.2 mm。此外,化合物1和2也有一种类似树脂的弱香气,它们有潜在的价值,可以用作香烟的香精。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Chemistry of Natural Compounds
Chemistry of Natural Compounds 化学-有机化学
CiteScore
1.40
自引率
25.00%
发文量
265
审稿时长
7.8 months
期刊介绍: Chemistry of Natural Compounds publishes reviews and general articles about the structure of different classes of natural compounds, the chemical characteristics of botanical families, genus, and species, to establish the comparative laws and connection between physiological activity and the structure of substances.
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