Philip W. Rouadi MD , Samar A. Idriss MD , Jean Bousquet MD, PhD , Mario Morais-Almeida MD , Cecilio R. Azar MD , Mona Sulaiman Al-Ahmad MD , Anahí Yáñez MD , Maryam Ali Y Al-Nesf MD, MSc , Talal M. Nsouli MD , Sami L. Bahna MD, DrPH , Eliane Abou-Jaoude MD , Fares H. Zaitoun MD , Usamah M. Hadi MD , Glenis K. Scadding MD , Peter K. Smith MBBS, PhD , René Maximiliano Gómez MD, PhD , Sandra N. González-Díaz MD, PhD , Ludger Klimek MD, PhD , Georges S. Juvelekian MD , Moussa A. Riachy MD , Ignacio J. Ansotegui MD, PhD
{"title":"WAO - ARIA consensus on chronic cough: Executive summary","authors":"Philip W. Rouadi MD , Samar A. Idriss MD , Jean Bousquet MD, PhD , Mario Morais-Almeida MD , Cecilio R. Azar MD , Mona Sulaiman Al-Ahmad MD , Anahí Yáñez MD , Maryam Ali Y Al-Nesf MD, MSc , Talal M. Nsouli MD , Sami L. Bahna MD, DrPH , Eliane Abou-Jaoude MD , Fares H. Zaitoun MD , Usamah M. Hadi MD , Glenis K. Scadding MD , Peter K. Smith MBBS, PhD , René Maximiliano Gómez MD, PhD , Sandra N. González-Díaz MD, PhD , Ludger Klimek MD, PhD , Georges S. Juvelekian MD , Moussa A. Riachy MD , Ignacio J. Ansotegui MD, PhD","doi":"10.1016/j.waojou.2025.101034","DOIUrl":null,"url":null,"abstract":"<div><div>Acute cough is a highly prevalent symptom in clinical practice. Chronic cough is a complex disease with significant impact on quality of life. The mechanistic pathways of chronic cough in cough-comorbid clinical phenotypes are elusive. Mounting evidence suggests presence of a hypersensitive cough reflex and implication of transient receptor potential channels and P2X receptors in cough neuronal pathways. Previously, the World Allergy Organization (WAO)/Allergic Rhinitis and its Impact on Asthma (ARIA) Joint Committee on Chronic Cough published updated experimental and clinical data on chronic cough, in addition to a multidisciplinary care pathway approach to its management. The goal of this manuscript is to provide clinicians with a succinct summary of chronic cough pathophysiology, clinical phenotypes, and management strategies in both primary and cough specialty care. This executive summary is a primer for clinicians on chronic cough. Increasing awareness on the topic among primary care physicians will improve the outcome of management of patients with chronic cough.</div></div>","PeriodicalId":54295,"journal":{"name":"World Allergy Organization Journal","volume":"18 3","pages":"Article 101034"},"PeriodicalIF":3.9000,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"World Allergy Organization Journal","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1939455125000092","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ALLERGY","Score":null,"Total":0}
引用次数: 0
Abstract
Acute cough is a highly prevalent symptom in clinical practice. Chronic cough is a complex disease with significant impact on quality of life. The mechanistic pathways of chronic cough in cough-comorbid clinical phenotypes are elusive. Mounting evidence suggests presence of a hypersensitive cough reflex and implication of transient receptor potential channels and P2X receptors in cough neuronal pathways. Previously, the World Allergy Organization (WAO)/Allergic Rhinitis and its Impact on Asthma (ARIA) Joint Committee on Chronic Cough published updated experimental and clinical data on chronic cough, in addition to a multidisciplinary care pathway approach to its management. The goal of this manuscript is to provide clinicians with a succinct summary of chronic cough pathophysiology, clinical phenotypes, and management strategies in both primary and cough specialty care. This executive summary is a primer for clinicians on chronic cough. Increasing awareness on the topic among primary care physicians will improve the outcome of management of patients with chronic cough.
期刊介绍:
The official pubication of the World Allergy Organization, the World Allergy Organization Journal (WAOjournal) publishes original mechanistic, translational, and clinical research on the topics of allergy, asthma, anaphylaxis, and clincial immunology, as well as reviews, guidelines, and position papers that contribute to the improvement of patient care. WAOjournal publishes research on the growth of allergy prevalence within the scope of single countries, country comparisons, and practical global issues and regulations, or threats to the allergy specialty. The Journal invites the submissions of all authors interested in publishing on current global problems in allergy, asthma, anaphylaxis, and immunology. Of particular interest are the immunological consequences of climate change and the subsequent systematic transformations in food habits and their consequences for the allergy/immunology discipline.