WAO - ARIA consensus on chronic cough: Executive summary

IF 3.9 2区医学 Q2 ALLERGY

World Allergy Organization Journal Pub Date : 2025-02-24 DOI:10.1016/j.waojou.2025.101034

Philip W. Rouadi MD , Samar A. Idriss MD , Jean Bousquet MD, PhD , Mario Morais-Almeida MD , Cecilio R. Azar MD , Mona Sulaiman Al-Ahmad MD , Anahí Yáñez MD , Maryam Ali Y Al-Nesf MD, MSc , Talal M. Nsouli MD , Sami L. Bahna MD, DrPH , Eliane Abou-Jaoude MD , Fares H. Zaitoun MD , Usamah M. Hadi MD , Glenis K. Scadding MD , Peter K. Smith MBBS, PhD , René Maximiliano Gómez MD, PhD , Sandra N. González-Díaz MD, PhD , Ludger Klimek MD, PhD , Georges S. Juvelekian MD , Moussa A. Riachy MD , Ignacio J. Ansotegui MD, PhD

{"title":"WAO - ARIA consensus on chronic cough: Executive summary","authors":"Philip W. Rouadi MD , Samar A. Idriss MD , Jean Bousquet MD, PhD , Mario Morais-Almeida MD , Cecilio R. Azar MD , Mona Sulaiman Al-Ahmad MD , Anahí Yáñez MD , Maryam Ali Y Al-Nesf MD, MSc , Talal M. Nsouli MD , Sami L. Bahna MD, DrPH , Eliane Abou-Jaoude MD , Fares H. Zaitoun MD , Usamah M. Hadi MD , Glenis K. Scadding MD , Peter K. Smith MBBS, PhD , René Maximiliano Gómez MD, PhD , Sandra N. González-Díaz MD, PhD , Ludger Klimek MD, PhD , Georges S. Juvelekian MD , Moussa A. Riachy MD , Ignacio J. Ansotegui MD, PhD","doi":"10.1016/j.waojou.2025.101034","DOIUrl":null,"url":null,"abstract":"<div><div>Acute cough is a highly prevalent symptom in clinical practice. Chronic cough is a complex disease with significant impact on quality of life. The mechanistic pathways of chronic cough in cough-comorbid clinical phenotypes are elusive. Mounting evidence suggests presence of a hypersensitive cough reflex and implication of transient receptor potential channels and P2X receptors in cough neuronal pathways. Previously, the World Allergy Organization (WAO)/Allergic Rhinitis and its Impact on Asthma (ARIA) Joint Committee on Chronic Cough published updated experimental and clinical data on chronic cough, in addition to a multidisciplinary care pathway approach to its management. The goal of this manuscript is to provide clinicians with a succinct summary of chronic cough pathophysiology, clinical phenotypes, and management strategies in both primary and cough specialty care. This executive summary is a primer for clinicians on chronic cough. Increasing awareness on the topic among primary care physicians will improve the outcome of management of patients with chronic cough.</div></div>","PeriodicalId":54295,"journal":{"name":"World Allergy Organization Journal","volume":"18 3","pages":"Article 101034"},"PeriodicalIF":3.9000,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"World Allergy Organization Journal","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1939455125000092","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ALLERGY","Score":null,"Total":0}

引用次数: 0

Abstract

Acute cough is a highly prevalent symptom in clinical practice. Chronic cough is a complex disease with significant impact on quality of life. The mechanistic pathways of chronic cough in cough-comorbid clinical phenotypes are elusive. Mounting evidence suggests presence of a hypersensitive cough reflex and implication of transient receptor potential channels and P2X receptors in cough neuronal pathways. Previously, the World Allergy Organization (WAO)/Allergic Rhinitis and its Impact on Asthma (ARIA) Joint Committee on Chronic Cough published updated experimental and clinical data on chronic cough, in addition to a multidisciplinary care pathway approach to its management. The goal of this manuscript is to provide clinicians with a succinct summary of chronic cough pathophysiology, clinical phenotypes, and management strategies in both primary and cough specialty care. This executive summary is a primer for clinicians on chronic cough. Increasing awareness on the topic among primary care physicians will improve the outcome of management of patients with chronic cough.

查看原文本刊更多论文

WAO - ARIA关于慢性咳嗽的共识：执行摘要

急性咳嗽是临床上非常普遍的症状。慢性咳嗽是一种严重影响生活质量的复杂疾病。慢性咳嗽在咳嗽共病临床表型中的机制途径尚不明确。越来越多的证据表明，在咳嗽神经元通路中存在超敏咳嗽反射和瞬态受体电位通道和P2X受体的含义。此前，世界过敏组织(WAO)/过敏性鼻炎及其对哮喘的影响（ARIA）慢性咳嗽联合委员会公布了最新的慢性咳嗽实验和临床数据，以及多学科治疗途径方法。这份手稿的目的是为临床医生提供慢性咳嗽病理生理、临床表型和初级和咳嗽专科护理管理策略的简明总结。本执行摘要是临床医生对慢性咳嗽的入门。提高初级保健医生对这一主题的认识将改善慢性咳嗽患者的管理结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

World Allergy Organization Journal Immunology and Microbiology-Immunology

CiteScore

9.10

自引率

5.90%

发文量

审稿时长

9 weeks

期刊介绍： The official pubication of the World Allergy Organization, the World Allergy Organization Journal (WAOjournal) publishes original mechanistic, translational, and clinical research on the topics of allergy, asthma, anaphylaxis, and clincial immunology, as well as reviews, guidelines, and position papers that contribute to the improvement of patient care. WAOjournal publishes research on the growth of allergy prevalence within the scope of single countries, country comparisons, and practical global issues and regulations, or threats to the allergy specialty. The Journal invites the submissions of all authors interested in publishing on current global problems in allergy, asthma, anaphylaxis, and immunology. Of particular interest are the immunological consequences of climate change and the subsequent systematic transformations in food habits and their consequences for the allergy/immunology discipline.