{"title":"Recent Advance in the Synthesis and Applications of Chiral Covalent Organic Frameworks: A Mini-Review","authors":"Qiuyi Liu, Zhu Li, Jing Sun, Yue Lan, Jiaqi Hu, Yuqiang Xiao, Feng-Qing Yang, Die Gao","doi":"10.1002/jssc.70101","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p>Chiral covalent organic frameworks (CCOFs) are emerging porous materials with tunable chiral structures, abundant pores, and high surface areas, gaining significant attentions in separation, sensing, and asymmetric catalysis. This review summarizes the synthesis methods of CCOFs and their applications in chiral recognition. It discusses the advantages and limitations of three synthesis strategies, including chiral post-modification, direct synthesis, and chiral-induced synthesis. The review also highlights the potential of CCOFs in chiral separation, sensing, and asymmetric catalysis for efficient purification, detection, and synthesis of chiral molecules. Challenges and future directions for the preparation and application of CCOFs are also addressed, aiming to guide further research and practical applications.</p>\n </div>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":"48 2","pages":""},"PeriodicalIF":2.8000,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of separation science","FirstCategoryId":"5","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/jssc.70101","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Chiral covalent organic frameworks (CCOFs) are emerging porous materials with tunable chiral structures, abundant pores, and high surface areas, gaining significant attentions in separation, sensing, and asymmetric catalysis. This review summarizes the synthesis methods of CCOFs and their applications in chiral recognition. It discusses the advantages and limitations of three synthesis strategies, including chiral post-modification, direct synthesis, and chiral-induced synthesis. The review also highlights the potential of CCOFs in chiral separation, sensing, and asymmetric catalysis for efficient purification, detection, and synthesis of chiral molecules. Challenges and future directions for the preparation and application of CCOFs are also addressed, aiming to guide further research and practical applications.
期刊介绍:
The Journal of Separation Science (JSS) is the most comprehensive source in separation science, since it covers all areas of chromatographic and electrophoretic separation methods in theory and practice, both in the analytical and in the preparative mode, solid phase extraction, sample preparation, and related techniques. Manuscripts on methodological or instrumental developments, including detection aspects, in particular mass spectrometry, as well as on innovative applications will also be published. Manuscripts on hyphenation, automation, and miniaturization are particularly welcome. Pre- and post-separation facets of a total analysis may be covered as well as the underlying logic of the development or application of a method.