{"title":"Eco-friendly synthesis trend of Sn-V bimetallic nanoparticles and its potential biological applications","authors":"Ramya Raman , Sudhahar Sakkarapani , Bhaskaran Arumugam","doi":"10.1016/j.matlet.2025.138277","DOIUrl":null,"url":null,"abstract":"<div><div>This investigation outlines the eco-conscious fabrication of tin-vanadium bimetallic nanoparticles (Sn-V BNPs) using <em>Piper longum</em> extract. The crystalline nature of Sn-V BNPs is confirmed by XRD data, with an average crystalline size of 20 nm. Morphological characterization by HRTEM confirms the irregular, polycrystalline structure of the nanoparticles, with an average size of approximately 25–50 nm. The Sn-V BNPs exhibit enhanced anti-inflammatory activity, achieving a maximum inhibition of 91.7 %. They demonstrate potent antidiabetic activity, with an IC<sub>50</sub> of 52 µg/mL in alpha-amylase inhibition. The nanoparticles also show remarkable cytotoxicity activity, with an IC<sub>50</sub> value of 57 µg/mL against MCF-7 lung cancer cells. These findings highlight the promising potential of green-synthesized bimetallic nanoparticles as multifunctional therapeutic agents.</div></div>","PeriodicalId":384,"journal":{"name":"Materials Letters","volume":"387 ","pages":"Article 138277"},"PeriodicalIF":2.7000,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Materials Letters","FirstCategoryId":"88","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0167577X25003064","RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
This investigation outlines the eco-conscious fabrication of tin-vanadium bimetallic nanoparticles (Sn-V BNPs) using Piper longum extract. The crystalline nature of Sn-V BNPs is confirmed by XRD data, with an average crystalline size of 20 nm. Morphological characterization by HRTEM confirms the irregular, polycrystalline structure of the nanoparticles, with an average size of approximately 25–50 nm. The Sn-V BNPs exhibit enhanced anti-inflammatory activity, achieving a maximum inhibition of 91.7 %. They demonstrate potent antidiabetic activity, with an IC50 of 52 µg/mL in alpha-amylase inhibition. The nanoparticles also show remarkable cytotoxicity activity, with an IC50 value of 57 µg/mL against MCF-7 lung cancer cells. These findings highlight the promising potential of green-synthesized bimetallic nanoparticles as multifunctional therapeutic agents.
期刊介绍:
Materials Letters has an open access mirror journal Materials Letters: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review.
Materials Letters is dedicated to publishing novel, cutting edge reports of broad interest to the materials community. The journal provides a forum for materials scientists and engineers, physicists, and chemists to rapidly communicate on the most important topics in the field of materials.
Contributions include, but are not limited to, a variety of topics such as:
• Materials - Metals and alloys, amorphous solids, ceramics, composites, polymers, semiconductors
• Applications - Structural, opto-electronic, magnetic, medical, MEMS, sensors, smart
• Characterization - Analytical, microscopy, scanning probes, nanoscopic, optical, electrical, magnetic, acoustic, spectroscopic, diffraction
• Novel Materials - Micro and nanostructures (nanowires, nanotubes, nanoparticles), nanocomposites, thin films, superlattices, quantum dots.
• Processing - Crystal growth, thin film processing, sol-gel processing, mechanical processing, assembly, nanocrystalline processing.
• Properties - Mechanical, magnetic, optical, electrical, ferroelectric, thermal, interfacial, transport, thermodynamic
• Synthesis - Quenching, solid state, solidification, solution synthesis, vapor deposition, high pressure, explosive