Campylobacter jejuni hepatitis in a horse: case report and literature review.

IF 1.2 3区 农林科学 Q3 VETERINARY SCIENCES
Melissa Macías-Rioseco, Jennine Ochoa, Eunju April Choi, Patricia Blanchard, Robert B Moeller, Francisco A Uzal
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引用次数: 0

Abstract

Campylobacter spp. can cause gastroenteritis, hepatitis, bacteremia, and abortions in domestic animals and humans. Some Campylobacter spp. are zoonotic. To our knowledge, hepatitis caused by Campylobacter jejuni has not been reported in horses. Here we present a case of acute necrosuppurative hepatitis caused by C. jejuni infection in a 3-y-old gelding, and we review the literature on C. jejuni infections in various animal species. The horse had a one-week history of weight loss and weakness before becoming recumbent and dying. Grossly, the liver had rounded edges and was mottled. There were ecchymoses on the gastric serosa, and a large amount of mucoid, pale, green-to-yellow content adhered to the mucosa of the small and large intestines. Microscopically, random areas in the liver were necrotic and infiltrated by large numbers of neutrophils, and fewer lymphocytes and plasma cells. Other changes in the liver included neutrophilic cholangitis with bile duct hyperplasia in portal areas, canalicular cholestasis, and mild portal fibrosis. The lamina propria, and occasionally the submucosa, of the small intestine and colon was infiltrated by large numbers of lymphocytes and plasma cells, and there was multifocal crypt necrosis. C. jejuni was recovered in pure culture from the liver.

一匹马的空肠弯曲菌肝炎:病例报告和文献综述。
弯曲杆菌可引起家畜和人类的肠胃炎、肝炎、菌血症和流产。有些弯曲杆菌属是人畜共患的。据我们所知,由空肠弯曲杆菌引起的肝炎尚未在马中报道。在这里,我们报告了一例由空肠梭菌感染引起的急性坏死性化脓性肝炎,发生在一匹3岁的骟马身上,我们回顾了有关各种动物空肠梭菌感染的文献。这匹马有一个星期的体重减轻和虚弱史,然后开始仰卧和死亡。肉眼可见,肝脏边缘圆润,呈斑驳状。胃浆膜有淤斑,小肠和大肠黏膜上有大量淡绿色至黄色黏液。镜下可见肝脏随机区域坏死,大量中性粒细胞浸润,淋巴细胞和浆细胞较少。肝脏的其他改变包括中性粒细胞胆管炎伴门静脉胆管增生、小管胆汁淤积和轻度门静脉纤维化。大量淋巴细胞和浆细胞浸润小肠和结肠固有层,偶见粘膜下层浸润,可见多灶性隐窝坏死。从肝脏中获得纯培养的空肠梭菌。
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来源期刊
CiteScore
3.00
自引率
6.70%
发文量
127
审稿时长
6-16 weeks
期刊介绍: The Journal of Veterinary Diagnostic Investigation (J Vet Diagn Invest) is an international peer-reviewed journal published bimonthly in English by the American Association of Veterinary Laboratory Diagnosticians (AAVLD). JVDI is devoted to all aspects of veterinary laboratory diagnostic science including the major disciplines of anatomic pathology, bacteriology/mycology, clinical pathology, epidemiology, immunology, laboratory information management, molecular biology, parasitology, public health, toxicology, and virology.
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