Rui Fu, Shipeng Zhang, Chang Cai, Xiaocui Wang, Yanjie Jiang, Xiulian Zhuang, Jiating Zhang, Xiaoli Ji, Chengcheng Yang
{"title":"Association between the intake of potentially risky beverages and the occurrence of endometrial polyps: a case-control study.","authors":"Rui Fu, Shipeng Zhang, Chang Cai, Xiaocui Wang, Yanjie Jiang, Xiulian Zhuang, Jiating Zhang, Xiaoli Ji, Chengcheng Yang","doi":"10.3389/fnut.2025.1538405","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>This case-control study aimed to examine the association between the frequency of potentially risky beverage consumption, levels of anxiety, and the prevalence of endometrial polyps.</p><p><strong>Methods: </strong>A total of 418 participants were enrolled in the study, comprising 206 cases and 212 controls. The case group consisted of patients who visited the gynecological clinic at the Affiliated Hospital of Chengdu University of Traditional Chinese Medicine and were diagnosed with endometrial polyps (Eps) based on international diagnostic criteria. The control group consisted of women of childbearing age who visited the gynecological clinic with similar clinical symptoms but did not have EPs. Basic information, consumption of potentially risky beverages (PRB), and anxiety levels for both groups were collected through a questionnaire survey. Finally, the relationship between the frequency of PRB consumption, anxiety levels, and the prevalence of EPs was evaluated.</p><p><strong>Results: </strong>In this study, we identified a significant positive association between the consumption of PRB and the prevalence of EPs. PRB intake was categorized into three groups based on the cumulative total score: 5-8 for the Low potentially risky beverages (LPRB) intake group, 9-12 for the medium potentially risky beverages (MPRB) intake group, and 13-21 for the high potentially risky beverages (HPRB) intake group. The results revealed that PRB consumption frequency was significantly associated with EPs (OR: 2.348, 95% CI: 1.153-4.78), with higher PRB intake correlating with an increased risk of EPs (<i>p</i>-value: 0.014). However, no significant difference was observed between the LPRB, MPRB, HPRB intake frequency groups and the different levels of anxiety (<i>p</i>-value: 0.793).</p><p><strong>Conclusion: </strong>Increased consumption of PRB was clearly associated with a greater risk of EPs, and over half of the participants exhibited varying degrees of anxiety. These findings suggest that the risk of EPs can be mitigated by controlling beverage intake and highlight the need for increased attention to women's mental health.</p><p><strong>Clinical trial registration: </strong>NCT06295510.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":"12 ","pages":"1538405"},"PeriodicalIF":4.0000,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832405/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Nutrition","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.3389/fnut.2025.1538405","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}
引用次数: 0
Abstract
Background: This case-control study aimed to examine the association between the frequency of potentially risky beverage consumption, levels of anxiety, and the prevalence of endometrial polyps.
Methods: A total of 418 participants were enrolled in the study, comprising 206 cases and 212 controls. The case group consisted of patients who visited the gynecological clinic at the Affiliated Hospital of Chengdu University of Traditional Chinese Medicine and were diagnosed with endometrial polyps (Eps) based on international diagnostic criteria. The control group consisted of women of childbearing age who visited the gynecological clinic with similar clinical symptoms but did not have EPs. Basic information, consumption of potentially risky beverages (PRB), and anxiety levels for both groups were collected through a questionnaire survey. Finally, the relationship between the frequency of PRB consumption, anxiety levels, and the prevalence of EPs was evaluated.
Results: In this study, we identified a significant positive association between the consumption of PRB and the prevalence of EPs. PRB intake was categorized into three groups based on the cumulative total score: 5-8 for the Low potentially risky beverages (LPRB) intake group, 9-12 for the medium potentially risky beverages (MPRB) intake group, and 13-21 for the high potentially risky beverages (HPRB) intake group. The results revealed that PRB consumption frequency was significantly associated with EPs (OR: 2.348, 95% CI: 1.153-4.78), with higher PRB intake correlating with an increased risk of EPs (p-value: 0.014). However, no significant difference was observed between the LPRB, MPRB, HPRB intake frequency groups and the different levels of anxiety (p-value: 0.793).
Conclusion: Increased consumption of PRB was clearly associated with a greater risk of EPs, and over half of the participants exhibited varying degrees of anxiety. These findings suggest that the risk of EPs can be mitigated by controlling beverage intake and highlight the need for increased attention to women's mental health.
期刊介绍：
No subject pertains more to human life than nutrition. The aim of Frontiers in Nutrition is to integrate major scientific disciplines in this vast field in order to address the most relevant and pertinent questions and developments. Our ambition is to create an integrated podium based on original research, clinical trials, and contemporary reviews to build a reputable knowledge forum in the domains of human health, dietary behaviors, agronomy & 21st century food science. Through the recognized open-access Frontiers platform we welcome manuscripts to our dedicated sections relating to different areas in the field of nutrition with a focus on human health.
Specialty sections in Frontiers in Nutrition include, for example, Clinical Nutrition, Nutrition & Sustainable Diets, Nutrition and Food Science Technology, Nutrition Methodology, Sport & Exercise Nutrition, Food Chemistry, and Nutritional Immunology. Based on the publication of rigorous scientific research, we thrive to achieve a visible impact on the global nutrition agenda addressing the grand challenges of our time, including obesity, malnutrition, hunger, food waste, sustainability and consumer health.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
