The effects of stigma and social support on the health-related quality of life of people with drug resistance tuberculosis in Lagos, Nigeria.

IF 3.3 3区医学 Q1 HEALTH CARE SCIENCES & SERVICES

Quality of Life Research Pub Date : 2025-02-18 DOI:10.1007/s11136-025-03902-5

Olusola Adedeji Adejumo, Champaklal Jinabhai, Olusoji Daniel, Firoza Haffejee

{"title":"The effects of stigma and social support on the health-related quality of life of people with drug resistance tuberculosis in Lagos, Nigeria.","authors":"Olusola Adedeji Adejumo, Champaklal Jinabhai, Olusoji Daniel, Firoza Haffejee","doi":"10.1007/s11136-025-03902-5","DOIUrl":null,"url":null,"abstract":"Purpose: This study assessed the effects of TB stigma and social support on the health-related quality of life (HRQoL) of people living with drug-resistant tuberculosis (DR-TB) in Lagos, Nigeria.Methods: A cross-sectional study was conducted in five DR-TB treatment centres in Lagos, Nigeria, between September and December 2023. A total of 203 adults on DR-TB treatment were recruited to complete a questionnaire including the Redwood DR-TB stigma scale, the Functional Assessment of Chronic Illness Therapy-TB (FACCIT) scale, and the Multidimensional Scale of Perceived Social Support (MSPSS). Student 't' test/one-way ANOVA, Pearson's correlation, and hierarchical linear regression analysis were conducted to explore the factors associated with HRQoL and the relationships between stigma, social support, and HRQoL.Results: The mean overall HRQoL was 41.1 ± 12.9 among people with DR-TB. The HRQoL score of the physical domain was the lowest (25.8 ± 13.8). Participants who were young, male, single, with higher education, and HIV-negative had higher HRQoL than their counterparts (p < 0.05). Stigma was negatively associated with HRQoL, while social support was positively related, collectively explaining 57.6% of the variance. In the final model, social support contributed more (B = 0.576) to predicting HRQoL than did stigma (B = - 0.414).Conclusion: The overall HRQoL of people with DR-TB in Lagos, Nigeria, was poor. Strategies that improve social support systems and reduce stigma are needed to improve this. Further studies are also required to assess the changes in HRQoL over time and evaluate the impact of specific stigma-reduction interventions.","PeriodicalId":20748,"journal":{"name":"Quality of Life Research","volume":" ","pages":""},"PeriodicalIF":3.3000,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Quality of Life Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11136-025-03902-5","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose: This study assessed the effects of TB stigma and social support on the health-related quality of life (HRQoL) of people living with drug-resistant tuberculosis (DR-TB) in Lagos, Nigeria.

Methods: A cross-sectional study was conducted in five DR-TB treatment centres in Lagos, Nigeria, between September and December 2023. A total of 203 adults on DR-TB treatment were recruited to complete a questionnaire including the Redwood DR-TB stigma scale, the Functional Assessment of Chronic Illness Therapy-TB (FACCIT) scale, and the Multidimensional Scale of Perceived Social Support (MSPSS). Student 't' test/one-way ANOVA, Pearson's correlation, and hierarchical linear regression analysis were conducted to explore the factors associated with HRQoL and the relationships between stigma, social support, and HRQoL.

Results: The mean overall HRQoL was 41.1 ± 12.9 among people with DR-TB. The HRQoL score of the physical domain was the lowest (25.8 ± 13.8). Participants who were young, male, single, with higher education, and HIV-negative had higher HRQoL than their counterparts (p < 0.05). Stigma was negatively associated with HRQoL, while social support was positively related, collectively explaining 57.6% of the variance. In the final model, social support contributed more (B = 0.576) to predicting HRQoL than did stigma (B = - 0.414).

Conclusion: The overall HRQoL of people with DR-TB in Lagos, Nigeria, was poor. Strategies that improve social support systems and reduce stigma are needed to improve this. Further studies are also required to assess the changes in HRQoL over time and evaluate the impact of specific stigma-reduction interventions.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Quality of Life Research 医学-公共卫生、环境卫生与职业卫生

CiteScore

6.50

自引率

8.60%

发文量

224

审稿时长

3-8 weeks

期刊介绍： Quality of Life Research is an international, multidisciplinary journal devoted to the rapid communication of original research, theoretical articles and methodological reports related to the field of quality of life, in all the health sciences. The journal also offers editorials, literature, book and software reviews, correspondence and abstracts of conferences. Quality of life has become a prominent issue in biometry, philosophy, social science, clinical medicine, health services and outcomes research. The journal''s scope reflects the wide application of quality of life assessment and research in the biological and social sciences. All original work is subject to peer review for originality, scientific quality and relevance to a broad readership. This is an official journal of the International Society of Quality of Life Research.