Striving Towards Equity in Cardiovascular Genomics Research.

IF 5.7 2区医学 Q1 PERIPHERAL VASCULAR DISEASE

Current Atherosclerosis Reports Pub Date : 2025-02-18 DOI:10.1007/s11883-025-01277-z

Javier Jurado Vélez, Nekayla Anderson, Ivree Datcher, Christy Foster, Pamela Jackson, Bertha Hidalgo

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引用次数: 0

Abstract

Purpose of review: Our review emphasizes recent advancements and persisting gaps in cardiovascular genomics, particularly highlighting how emerging studies involving underrepresented populations have uncovered new genetic variants associated with cardiovascular diseases.

Recent findings: Initiatives like the H3Africa project, the Million Veterans Program, and the All of Us Research Program are working to address this gap by focusing on underrepresented groups. Additionally, emerging research is centering on the interplay between genetic factors and socio-environmental determinants of health, which disproportionately impact marginalized communities. As cardiovascular genomics research grows, increasing the inclusion of underrepresented populations is essential for gaining a more comprehensive understanding of genetic variability. This will lead to more accurate and clinically meaningful strategies for preventing and treating cardiovascular diseases across all ancestral backgrounds and diverse populations.

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努力实现心血管基因组学研究的公平性。

综述目的：我们的综述强调心血管基因组学的最新进展和持续存在的差距，特别强调涉及代表性不足的人群的新兴研究如何发现与心血管疾病相关的新遗传变异。最近的发现：诸如h3非洲项目、百万退伍军人项目和我们所有人研究项目等倡议正在努力通过关注代表性不足的群体来解决这一差距。此外，新兴研究的重点是遗传因素与健康的社会环境决定因素之间的相互作用，这对边缘化社区的影响尤为严重。随着心血管基因组学研究的发展，增加代表性不足人群的纳入对于获得更全面的遗传变异性理解至关重要。这将导致在所有祖先背景和不同人群中预防和治疗心血管疾病的更准确和临床有意义的策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Atherosclerosis Reports 医学-

CiteScore

9.00

自引率

3.40%

发文量

审稿时长

6-12 weeks

期刊介绍： The aim of this journal is to systematically provide expert views on current basic science and clinical advances in the field of atherosclerosis and highlight the most important developments likely to transform the field of cardiovascular prevention, diagnosis, and treatment. We accomplish this aim by appointing major authorities to serve as Section Editors who select leading experts from around the world to provide definitive reviews on key topics and papers published in the past year. We also provide supplementary reviews and commentaries from well-known figures in the field. An Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research.