Neurogenesis altered by disease and stimulation

IF 28.2 1区医学 Q1 CLINICAL NEUROLOGY

Nature Reviews Neurology Pub Date : 2025-02-17 DOI:10.1038/s41582-025-01068-9

Ian Fyfe

引用次数: 0

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神经发生因疾病和刺激而改变

新的研究表明，脑室下区（SVZ）的神经发生在神经退行性疾病中发生改变，并被深部脑刺激激活。对死后脑组织的分析表明，帕金森病患者的SVZ比没有神经退行性疾病的人更薄。相比之下，亨廷顿病患者和接受深部脑刺激的PD患者的SVZ更厚。在这两种情况下，SVZ的增厚都伴随着高密度的成体神经干细胞，表明神经发生的激活。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Neurology 医学-临床神经学

CiteScore

29.90

自引率

0.80%

发文量

138

审稿时长

6-12 weeks

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