Minimally-invasive common-path OCT system for neurosurgery applications.

IF 2.9 2区 医学 Q2 BIOCHEMICAL RESEARCH METHODS
Biomedical optics express Pub Date : 2025-01-31 eCollection Date: 2025-02-01 DOI:10.1364/BOE.549160
Gary Evans, Jerome Gandar, Simon Thiele, David J Segar, Yoseline Rosales Cabara, Matthew Lapinski, Ivana Gantar, Thierry Campiche, Corinne Brana, Michalina J Gora, Jules Scholler
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引用次数: 0

Abstract

We present a minimally-invasive common-path optical coherence tomography (OCT) system operating at 1310 nm with a novel forward viewing monolithic endoscope designed specifically for neurosurgical applications with real-time 3D imaging capabilities. This system's real-time tissue identification capability could enhance the accuracy of stereotactic surgeries, including deep brain stimulation and biopsy, while its ability to detect blood flow could significantly reduce the risk of hemorrhage. The system was successfully tested in vivo in a rabbit cohort.

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来源期刊
Biomedical optics express
Biomedical optics express BIOCHEMICAL RESEARCH METHODS-OPTICS
CiteScore
6.80
自引率
11.80%
发文量
633
审稿时长
1 months
期刊介绍: The journal''s scope encompasses fundamental research, technology development, biomedical studies and clinical applications. BOEx focuses on the leading edge topics in the field, including: Tissue optics and spectroscopy Novel microscopies Optical coherence tomography Diffuse and fluorescence tomography Photoacoustic and multimodal imaging Molecular imaging and therapies Nanophotonic biosensing Optical biophysics/photobiology Microfluidic optical devices Vision research.
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