Soft elastomeric optical fibers for oxygen change measurements of blood and living tissues: a thermoplastic polyurethane assessment.

IF 2.9 2区 医学 Q2 BIOCHEMICAL RESEARCH METHODS
Biomedical optics express Pub Date : 2025-01-06 eCollection Date: 2025-02-01 DOI:10.1364/BOE.549790
Miguel Llera, Edith Laux, Frédéric Flahaut, Laure Jeandupeux, Esteban Alvarez Seoane, Maxime Zerbib, Jean-Charles Beugnot, Philippe Potty
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引用次数: 0

Abstract

This paper discusses the design, fabrication, and use of thermoplastic polyurethane optical fibers intended for oxygen saturation measurements. It includes an evaluation of the fiber attenuation and the creation of two probes for the measurement assessment. For comparison, a third probe is made using conventional glass optical fibers. The assessment is conducted in two stages: first, absorption measurements are performed using a mixture of methylene blue and intralipid diluted in deionized water; second, a measurement with human blood is conducted to demonstrate the effectiveness of such fibers in measuring blood oxygen saturation. Additionally, a comprehensive study of measurement stability is provided.

血液和活组织氧变化测量用软弹性光纤:热塑性聚氨酯评估。
本文讨论了用于氧饱和度测量的热塑性聚氨酯光纤的设计、制造和使用。它包括对光纤衰减的评估和用于测量评估的两个探头的创建。为了比较,第三个探头是用传统的玻璃光纤制成的。评估分两个阶段进行:首先,使用去离子水稀释的亚甲基蓝和脂内的混合物进行吸收测量;其次,用人体血液进行测量,以证明这种纤维在测量血氧饱和度方面的有效性。此外,还对测量稳定性进行了全面的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biomedical optics express
Biomedical optics express BIOCHEMICAL RESEARCH METHODS-OPTICS
CiteScore
6.80
自引率
11.80%
发文量
633
审稿时长
1 months
期刊介绍: The journal''s scope encompasses fundamental research, technology development, biomedical studies and clinical applications. BOEx focuses on the leading edge topics in the field, including: Tissue optics and spectroscopy Novel microscopies Optical coherence tomography Diffuse and fluorescence tomography Photoacoustic and multimodal imaging Molecular imaging and therapies Nanophotonic biosensing Optical biophysics/photobiology Microfluidic optical devices Vision research.
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