An expert's guide to classical manometric patterns seen in high-resolution colonic manometry.

IF 3.8 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Expert Review of Gastroenterology & Hepatology Pub Date : 2025-02-27 DOI:10.1080/17474124.2025.2468301

Phil G Dinning

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引用次数: 0

Abstract

Introduction: High-resolution colonic manometry is a research and diagnostic tool used to evaluate colonic motility. Used in health it helps us understand normal colonic motility and the colonic response to physiological stimuli such as meal, as well as chemical (laxatives) and mechanical (distension) stimuli. In pediatric and adult patients with suspected colonic disorders, it can help to understand the abnormal colonic motility associated with the condition.

Area covered: High-resolution manometric catheters contain multiple closely spaced sensors that detect intraluminal pressure changes and contractile force, which can be interpreted as contractile activity. This activity forms several distinctive motor patterns that help in understanding normal colonic physiology and provide insights into the potential pathophysiology underlying colonic disorders such as constipation. After a PubMed search of colonic high-resolution manometry studies, this review provides an overview of the characterized motor patterns, when they occur, how they are initiated, their clinical relevance, and their role, if any, in guiding therapeutic interventions.

Expert opinion: High-resolution colonic manometry has identified motor patterns that were missed or mislabeled by low-resolution recordings. How best to use this information to guide treatment remains to be determined.

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介绍：高分辨率结肠测压是一种用于评估结肠运动的研究和诊断工具。对于健康人，它有助于我们了解正常的结肠运动以及结肠对生理刺激（如进餐）、化学刺激（泻药）和机械刺激（胀气）的反应。对于疑似结肠疾病的儿童和成人患者，它有助于了解与结肠疾病相关的结肠运动异常：高分辨率测压导管包含多个紧密间隔的传感器，可检测到管腔内压力变化和收缩力，这可解释为收缩活动。这种活动形成几种独特的运动模式，有助于了解正常的结肠生理学，并为了解便秘等结肠疾病的潜在病理生理学提供见解。在对 Pubmed 上的结肠高分辨率测压研究进行搜索后，本综述概述了这些运动模式的特征、发生时间、启动方式、临床相关性以及在指导治疗干预方面的作用（如果有的话）：专家观点：高分辨率结肠测压发现了被低分辨率记录遗漏或错误标记的运动模式。如何更好地利用这些信息指导治疗仍有待确定。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Expert Review of Gastroenterology & Hepatology GASTROENTEROLOGY & HEPATOLOGY-

CiteScore

6.80

自引率

2.60%

发文量

审稿时长

6-12 weeks

期刊介绍： The enormous health and economic burden of gastrointestinal disease worldwide warrants a sharp focus on the etiology, epidemiology, prevention, diagnosis, treatment and development of new therapies. By the end of the last century we had seen enormous advances, both in technologies to visualize disease and in curative therapies in areas such as gastric ulcer, with the advent first of the H2-antagonists and then the proton pump inhibitors - clear examples of how advances in medicine can massively benefit the patient. Nevertheless, specialists face ongoing challenges from a wide array of diseases of diverse etiology.