Does the application protocol influence the masking effect of resin infiltration on MIH opacities? Systematic review and meta-analysis

IF 4.8 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of dentistry Pub Date : 2025-02-11 DOI:10.1016/j.jdent.2025.105617

Natália de Araújo Prado , Roberta Costa Jorge , Rudá França Moreira , Susanne Effenberger , Marcus Cebula , Tatiana Kelly da Silva Fidalgo , Vera Mendes Soviero

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引用次数: 0

Abstract

Objective

To compile the available evidence on the effectiveness of resin infiltration in masking demarcated opacities in permanent incisors with MIH and whether modifications to the treatment protocol impact the outcome.

Data sources and study selection

This review followed PRISMA2020 and was registered in PROSPERO (CRD42023414048). Searches were performed in MedLine, LILACS, BBO, Cochrane, Web of Science, Scopus, Embase, OpenGrey, and Google Scholar, by two independent reviewers. JBI and RoB2 were used to evaluate risk of bias. R software was used to perform meta-analyses.

Results

Eight uncontrolled, two non-randomized, and two RCTs evaluated 369 teeth in 6–31year-old participants. Six studies followed the standard resin infiltration protocol, while the others reported modifications. The meta-analysis estimated an overall proportion of total masking of 37 % (CI: 18–55). Modified protocols tended to achieve higher success rates (40 %; CI: 9–72) compared to standard protocols (30 %; CI: 17–44), though this difference was not statistically significant. The overall reduction in ΔE was 3.08 (CI: 0.74–5.42), with 1.54 (CI: 0.68–2.40) for standard protocols and 3.84 (CI: 0.80–6.89) for modified ones. Seven studies had moderate risk of bias, and three had high risk. The certainty of evidence was low due to heterogeneity (I² > 80 %) and imprecision concerns.

Conclusion

Resin infiltration is effective in reducing the color difference between MIH opacity and normal enamel. The achievement of total masking was not significantly different between the standard and modified protocols. Heterogeneity and lack of controlled studies limit the certainty of evidence.

Clinical significance

This review reinforces the effectiveness of resin infiltration in reducing the color difference between MIH opacity and normal enamel. Modifications in the protocol improved the infiltration but were not enough to be significantly superior. This review contributes to the understanding of peculiarities related to the microinvasive esthetic treatment of MIH.

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来源期刊

Journal of dentistry 医学-牙科与口腔外科

CiteScore

7.30

自引率

11.40%

发文量

349

审稿时长

35 days

期刊介绍： The Journal of Dentistry has an open access mirror journal The Journal of Dentistry: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. The Journal of Dentistry is the leading international dental journal within the field of Restorative Dentistry. Placing an emphasis on publishing novel and high-quality research papers, the Journal aims to influence the practice of dentistry at clinician, research, industry and policy-maker level on an international basis. Topics covered include the management of dental disease, periodontology, endodontology, operative dentistry, fixed and removable prosthodontics, dental biomaterials science, long-term clinical trials including epidemiology and oral health, technology transfer of new scientific instrumentation or procedures, as well as clinically relevant oral biology and translational research. The Journal of Dentistry will publish original scientific research papers including short communications. It is also interested in publishing review articles and leaders in themed areas which will be linked to new scientific research. Conference proceedings are also welcome and expressions of interest should be communicated to the Editor.